284398

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 313222..313858 Replicon chromosome
Accession NZ_CP128196
Organism Neobacillus mesonae strain NS-6

Toxin (Protein)


Gene name mazF Uniprot ID A0A3Q9QS43
Locus tag P3L48_RS01625 Protein ID WP_041967053.1
Coordinates 313508..313858 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag P3L48_RS01620 Protein ID WP_191276993.1
Coordinates 313222..313503 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P3L48_RS01600 309464..310045 - 582 WP_286230441.1 rhomboid family intramembrane serine protease -
P3L48_RS01605 310136..310486 + 351 WP_286230442.1 holo-ACP synthase -
P3L48_RS01610 310651..311658 + 1008 WP_286230443.1 DUF4367 domain-containing protein -
P3L48_RS01615 311780..312943 + 1164 WP_286230444.1 alanine racemase -
P3L48_RS01620 313222..313503 + 282 WP_191276993.1 YlcI/YnfO family protein Antitoxin
P3L48_RS01625 313508..313858 + 351 WP_041967053.1 type II toxin-antitoxin system endoribonuclease NdoA Toxin
P3L48_RS01630 314030..316201 + 2172 WP_286230445.1 Tex family protein -
P3L48_RS01635 316222..316335 - 114 WP_127484595.1 cortex morphogenetic protein CmpA -
P3L48_RS01640 316433..316912 + 480 WP_127484597.1 SprT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13020.06 Da        Isoelectric Point: 4.8998

>T284398 WP_041967053.1 NZ_CP128196:313508-313858 [Neobacillus mesonae]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIIAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMEKVDEALQVSLGLIEF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10866.36 Da        Isoelectric Point: 7.2029

>AT284398 WP_191276993.1 NZ_CP128196:313222-313503 [Neobacillus mesonae]
VSESSATTEILVKLPQHLLTELDGFVKQENVNRSEFIYQATKMYLRERKQRQIRESMRRGYMEMAKINLRIASEAFQAEY
EAEHTVERLVSGG

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Q9QS43

Antitoxin

Source ID Structure

References