Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3071478..3071623 Replicon chromosome
Accession NZ_CP128191
Organism Klebsiella pneumoniae strain KP0714

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3071485..3071587 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3071478..3071623 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSG82_RS15485 (QSG82_15485) 3067010..3068443 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
QSG82_RS15490 (QSG82_15490) 3068559..3068798 + 240 WP_002911393.1 YebV family protein -
QSG82_RS15495 (QSG82_15495) 3068896..3069087 + 192 WP_002911395.1 YebW family protein -
QSG82_RS15500 (QSG82_15500) 3069084..3069737 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
QSG82_RS15505 (QSG82_15505) 3069894..3070862 + 969 WP_004151446.1 VirK/YbjX family protein -
QSG82_RS15510 (QSG82_15510) 3070967..3071110 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3071478..3071623 + 146 - - Antitoxin
- 3071485..3071587 - 103 - - Toxin
QSG82_RS15515 (QSG82_15515) 3071746..3072084 - 339 WP_002911404.1 YebY family protein -
QSG82_RS15520 (QSG82_15520) 3072101..3072970 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
QSG82_RS15525 (QSG82_15525) 3072974..3073348 - 375 WP_004151448.1 CopC domain-containing protein YobA -
QSG82_RS15530 (QSG82_15530) 3073461..3073691 + 231 WP_002911406.1 DNA polymerase III subunit theta -
QSG82_RS15535 (QSG82_15535) 3073770..3074429 + 660 WP_002911407.1 exodeoxyribonuclease X -
QSG82_RS15540 (QSG82_15540) 3074433..3076493 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T284380 NZ_CP128191:c3071587-3071485 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT284380 NZ_CP128191:3071478-3071623 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References