284370

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1218747..1219664 Replicon chromosome
Accession NZ_CP128184
Organism Bacillus velezensis strain YJ0-1 isolate soil

Toxin (Protein)


Gene name spoIISA Uniprot ID I2HQ15
Locus tag QRA13_RS05335 Protein ID WP_007407256.1
Coordinates 1218747..1219493 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag QRA13_RS05340 Protein ID WP_003154807.1
Coordinates 1219494..1219664 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRA13_RS05315 (QRA13_05315) 1214139..1215089 - 951 WP_224224209.1 ring-cleaving dioxygenase -
QRA13_RS05320 (QRA13_05320) 1215412..1216728 + 1317 WP_224224208.1 amino acid permease -
QRA13_RS05325 (QRA13_05325) 1217014..1217631 + 618 WP_032874614.1 DUF47 domain-containing protein -
QRA13_RS05330 (QRA13_05330) 1217644..1218642 + 999 WP_044802872.1 inorganic phosphate transporter -
QRA13_RS05335 (QRA13_05335) 1218747..1219493 + 747 WP_007407256.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QRA13_RS05340 (QRA13_05340) 1219494..1219664 + 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QRA13_RS05345 (QRA13_05345) 1219761..1219886 + 126 WP_003154809.1 hypothetical protein -
QRA13_RS05350 (QRA13_05350) 1219921..1220799 - 879 WP_007407257.1 N-acetylmuramoyl-L-alanine amidase -
QRA13_RS05355 (QRA13_05355) 1220813..1221076 - 264 WP_003154813.1 phage holin -
QRA13_RS05360 (QRA13_05360) 1221090..1221353 - 264 WP_003154815.1 hemolysin XhlA family protein -
QRA13_RS05365 (QRA13_05365) 1221406..1222167 - 762 WP_045207175.1 hypothetical protein -
QRA13_RS05370 (QRA13_05370) 1222224..1222421 - 198 WP_007610833.1 XkdX family protein -
QRA13_RS05375 (QRA13_05375) 1222426..1222797 - 372 WP_032874603.1 XkdW family protein -
QRA13_RS05380 (QRA13_05380) 1222810..1224432 - 1623 WP_224224207.1 pyocin knob domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29077.57 Da        Isoelectric Point: 4.7755

>T284370 WP_007407256.1 NZ_CP128184:1218747-1219493 [Bacillus velezensis]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT284370 WP_003154807.1 NZ_CP128184:1219494-1219664 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB I2HQ15

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References