Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 266071..266719 Replicon chromosome
Accession NZ_CP128182
Organism Stenotrophomonas maltophilia strain a7

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QP025_RS01215 Protein ID WP_005407702.1
Coordinates 266071..266376 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag QP025_RS01220 Protein ID WP_005407703.1
Coordinates 266417..266719 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP025_RS01185 262025..262816 - 792 WP_197569412.1 zinc-dependent peptidase -
QP025_RS01190 262783..263061 - 279 WP_005407696.1 hypothetical protein -
QP025_RS01195 263206..264171 + 966 WP_043035430.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
QP025_RS01200 264168..264899 + 732 WP_005407698.1 type III pantothenate kinase -
QP025_RS01205 264909..265763 + 855 WP_005411958.1 SPOR domain-containing protein -
QP025_RS01215 266071..266376 + 306 WP_005407702.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QP025_RS01220 266417..266719 + 303 WP_005407703.1 putative addiction module antidote protein Antitoxin
QP025_RS01225 266977..267276 - 300 WP_005407704.1 hypothetical protein -
QP025_RS01230 267357..267764 - 408 WP_005407705.1 hypothetical protein -
QP025_RS01235 268359..269129 + 771 WP_005411960.1 DUF3011 domain-containing protein -
QP025_RS01240 269154..269501 - 348 WP_049454229.1 hypothetical protein -
QP025_RS01245 269632..270552 + 921 WP_201863758.1 arginase -
QP025_RS01250 270713..270850 + 138 WP_005407710.1 entericidin A/B family lipoprotein -
QP025_RS01255 271057..271278 + 222 WP_004153772.1 CsbD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-95)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11444.15 Da        Isoelectric Point: 10.9897

>T284369 WP_005407702.1 NZ_CP128182:266071-266376 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLAEGHPGDHRYLADGVSELRIDAGPGYRVYYTQRGRQLVILLVGGDKGS
QQRDIEKAKEIARALRASNWL

Download         Length: 306 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10703.27 Da        Isoelectric Point: 7.2780

>AT284369 WP_005407703.1 NZ_CP128182:266417-266719 [Stenotrophomonas maltophilia]
MAIKKKVELEAFDVAEHLHTPKEMAAYLDACIEESDGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FSTILKVTRALGVRLHASAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References