Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2430918..2431911 Replicon chromosome
Accession NZ_CP128153
Organism Bacillus sp. DX3.1

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag QRE67_RS11905 Protein ID WP_286125028.1
Coordinates 2430918..2431658 (+) Length 247 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag QRE67_RS11910 Protein ID WP_286125029.1
Coordinates 2431783..2431911 (+) Length 43 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRE67_RS11885 (QRE67_11875) 2426085..2427476 + 1392 WP_286125024.1 FAD-linked oxidase C-terminal domain-containing protein -
QRE67_RS11890 (QRE67_11880) 2427619..2429298 - 1680 WP_286125025.1 alpha-keto acid decarboxylase family protein -
QRE67_RS11895 (QRE67_11885) 2429403..2429885 + 483 WP_286125026.1 helix-turn-helix domain-containing protein -
QRE67_RS11900 (QRE67_11890) 2429980..2430744 + 765 WP_286125027.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
QRE67_RS11905 (QRE67_11895) 2430918..2431658 + 741 WP_286125028.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QRE67_RS11910 (QRE67_11900) 2431783..2431911 + 129 WP_286125029.1 D-alanyl-D-alanine carboxypeptidase Antitoxin
QRE67_RS11915 (QRE67_11905) 2431997..2432173 + 177 WP_286125030.1 stage II sporulation protein SB -
QRE67_RS11920 (QRE67_11910) 2432335..2432517 + 183 WP_286125031.1 hypothetical protein -
QRE67_RS11925 (QRE67_11915) 2432587..2433042 + 456 WP_286125032.1 hypothetical protein -
QRE67_RS11930 (QRE67_11920) 2433257..2433856 - 600 WP_286125033.1 undecaprenyl-diphosphatase -
QRE67_RS11935 (QRE67_11925) 2434471..2435937 + 1467 WP_286125034.1 aminoacyl-histidine dipeptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(10-244)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 247 a.a.        Molecular weight: 28426.22 Da        Isoelectric Point: 8.2883

>T284365 WP_286125028.1 NZ_CP128153:2430918-2431658 [Bacillus sp. DX3.1]
MTVSNIRIGLFLLVVAFLFLILFYWKNEELYEEKKQLIRKTWYGVFISTVTVYFMVKGIDLTLWKNILMFVAMVIFVDIA
FILTPNISEIWGAKFSDIGRTVQSIKRSLIASKARGEIYTTLIQNVNPAAFGRMEWRTEAEYAESLNAFLDTYAEKIGAK
VVVFVASDELNTNFRGVRSQFSIMLPLEHIEKLNEQKAVQVENVGIIPVKILKDVFIVIDGQKNNLQDRDFENVYNLTIH
HSYFSK

Download         Length: 741 bp


Antitoxin


Download         Length: 43 a.a.        Molecular weight: 5012.44 Da        Isoelectric Point: 4.0338

>AT284365 WP_286125029.1 NZ_CP128153:2431783-2431911 [Bacillus sp. DX3.1]
VEKQYDNDFFKEEKDDATDFSLIKGDTMQQVEDLEEELKRKG

Download         Length: 129 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References