284363

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2372597..2373572 Replicon chromosome
Accession NZ_CP128152
Organism Bacillus albus strain SXL388

Toxin (Protein)


Gene name spoIISA Uniprot ID A0A1J9UQ45
Locus tag QRY64_RS14685 Protein ID WP_071756939.1
Coordinates 2372597..2373334 (+) Length 246 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1S9U9H9
Locus tag QRY64_RS14690 Protein ID WP_048529988.1
Coordinates 2373447..2373572 (+) Length 42 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRY64_RS14655 (QRY64_14645) 2367804..2367887 + 84 Protein_2341 ABC transporter ATP-binding protein -
QRY64_RS14660 (QRY64_14650) 2367946..2368656 + 711 WP_128974812.1 class I SAM-dependent methyltransferase -
QRY64_RS14665 (QRY64_14655) 2368777..2369184 + 408 WP_071756918.1 VOC family protein -
QRY64_RS14670 (QRY64_14660) 2369229..2370914 - 1686 WP_270797182.1 alpha-keto acid decarboxylase family protein -
QRY64_RS14675 (QRY64_14665) 2371022..2371504 + 483 WP_048529992.1 MarR family winged helix-turn-helix transcriptional regulator -
QRY64_RS14680 (QRY64_14670) 2371671..2372408 + 738 WP_071756916.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
QRY64_RS14685 (QRY64_14675) 2372597..2373334 + 738 WP_071756939.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QRY64_RS14690 (QRY64_14680) 2373447..2373572 + 126 WP_048529988.1 hypothetical protein Antitoxin
QRY64_RS14695 (QRY64_14685) 2373648..2373824 + 177 WP_000852620.1 stage II sporulation protein SB -
QRY64_RS14700 (QRY64_14690) 2373843..2374231 - 389 Protein_2350 YxeA family protein -
QRY64_RS14705 (QRY64_14695) 2374448..2375917 + 1470 WP_270797184.1 beta-Ala-His dipeptidase -
QRY64_RS14710 (QRY64_14700) 2376503..2376973 - 471 WP_048529981.1 DUF5065 family protein -
QRY64_RS14715 (QRY64_14705) 2377427..2378086 + 660 WP_270797185.1 CatB-related O-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(9-243)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 246 a.a.        Molecular weight: 28369.00 Da        Isoelectric Point: 8.3034

>T284363 WP_071756939.1 NZ_CP128152:2372597-2373334 [Bacillus albus]
VISNIRIGLFILAIVFLVLVFFYWRNEELYEEKKQRIRKTWYGLFIVSVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEDYTKSLNAFLDSYGEKIGAKI
VVFESAKELNTNFRGIRSQFSTIVPFEHIEQLNEQKAVQVENVGIIPVKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK

Download         Length: 738 bp

Antitoxin


Download         Length: 42 a.a.        Molecular weight: 4908.32 Da        Isoelectric Point: 3.9150

>AT284363 WP_048529988.1 NZ_CP128152:2373447-2373572 [Bacillus albus]
VIKDYDNDFFKEDNEDATDFSLIKGDTLQQVEELEEELKRK

Download         Length: 126 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J9UQ45

Antitoxin

Source ID Structure
AlphaFold DB A0A1S9U9H9

References