284362

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 239726..240368 Replicon chromosome
Accession NZ_CP128152
Organism Bacillus albus strain SXL388

Toxin (Protein)


Gene name pemK Uniprot ID J8CWW5
Locus tag QRY64_RS03700 Protein ID WP_000635963.1
Coordinates 240018..240368 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID R8I8H2
Locus tag QRY64_RS03695 Protein ID WP_000004570.1
Coordinates 239726..240013 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRY64_RS03670 (QRY64_03660) 234896..235858 + 963 WP_048529174.1 UV DNA damage repair endonuclease UvsE -
QRY64_RS03675 (QRY64_03665) 236020..236568 - 549 WP_048529176.1 rhomboid family intramembrane serine protease -
QRY64_RS03680 (QRY64_03670) 236661..237020 + 360 WP_048529178.1 holo-ACP synthase -
QRY64_RS03685 (QRY64_03675) 237177..238127 + 951 WP_002096914.1 outer membrane lipoprotein carrier protein LolA -
QRY64_RS03690 (QRY64_03680) 238246..239415 + 1170 WP_048529179.1 alanine racemase -
QRY64_RS03695 (QRY64_03685) 239726..240013 + 288 WP_000004570.1 antitoxin EndoAI Antitoxin
QRY64_RS03700 (QRY64_03690) 240018..240368 + 351 WP_000635963.1 type II toxin-antitoxin system endoribonuclease NdoA Toxin
QRY64_RS03705 (QRY64_03695) 240437..242605 + 2169 WP_071757098.1 Tex family protein -
QRY64_RS03710 (QRY64_03700) 242664..242780 - 117 WP_001143642.1 cortex morphogenetic protein CmpA -
QRY64_RS03715 (QRY64_03705) 242976..243434 + 459 WP_048529183.1 SprT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12974.12 Da        Isoelectric Point: 5.7168

>T284362 WP_000635963.1 NZ_CP128152:240018-240368 [Bacillus albus]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKKYGFERDSVILLEQI
RTIDKQRLTDKITHLDEVMMIRVDEALQISLGLIDF

Download         Length: 351 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10780.36 Da        Isoelectric Point: 8.9605

>AT284362 WP_000004570.1 NZ_CP128152:239726-240013 [Bacillus albus]
VSESSVTTEIVVRLPKQMVTELDGIGKQENKNRHELICQATQLLLRQHKTKKRYQHESMRRGYIEMGKINLGIASEAFLA
EYEAAHTVERLVSGG

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 4HKE
PDB 7BXY

Antitoxin

Source ID Structure
AlphaFold DB A0A366FY90

References