284352

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yxiD-yxxD/-
Location 1789412..1790163 Replicon chromosome
Accession NZ_CP128114
Organism Bacillus safensis strain G6S3

Toxin (Protein)


Gene name yxiD Uniprot ID -
Locus tag QRD88_RS09150 Protein ID WP_286099128.1
Coordinates 1789852..1790163 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name yxxD Uniprot ID -
Locus tag QRD88_RS09145 Protein ID WP_056766693.1
Coordinates 1789412..1789852 (-) Length 147 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRD88_RS09120 (QRD88_09115) 1784528..1785400 - 873 WP_212051856.1 LysR family transcriptional regulator -
QRD88_RS09125 (QRD88_09120) 1785579..1786779 - 1201 Protein_1743 FAD-binding protein -
QRD88_RS09130 (QRD88_09125) 1787118..1788080 - 963 WP_286099127.1 HTH domain-containing protein -
QRD88_RS09135 (QRD88_09130) 1788189..1788668 + 480 WP_212051850.1 GyrI-like domain-containing protein -
QRD88_RS09140 (QRD88_09135) 1788690..1789154 + 465 WP_024425197.1 hypothetical protein -
QRD88_RS09145 (QRD88_09140) 1789412..1789852 - 441 WP_056766693.1 SMI1/KNR4 family protein Antitoxin
QRD88_RS09150 (QRD88_09145) 1789852..1790163 - 312 WP_286099128.1 hypothetical protein Toxin
QRD88_RS09155 (QRD88_09150) 1790160..1791485 - 1326 WP_286099129.1 T7SS effector LXG polymorphic toxin -
QRD88_RS09160 (QRD88_09155) 1791847..1792266 - 420 WP_044335851.1 MarR family transcriptional regulator -
QRD88_RS09165 (QRD88_09160) 1792437..1793957 + 1521 WP_212053044.1 MDR family MFS transporter -
QRD88_RS09170 (QRD88_09165) 1793996..1794865 - 870 WP_024427782.1 class II fructose-bisphosphate aldolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 104 a.a.        Molecular weight: 11906.40 Da        Isoelectric Point: 9.7706

>T284352 WP_286099128.1 NZ_CP128114:c1790163-1789852 [Bacillus safensis]
MTPIETAKHRAEFDKVKNTVIKKWEENTGQKWPEYNENVISEKTGKIIRKKGDKYDAHHIIENTFGGEHEWWNMHPAKFP
NEHQAGIHGKGSPANELFKGGKK

Download         Length: 312 bp


Antitoxin


Download         Length: 147 a.a.        Molecular weight: 17527.56 Da        Isoelectric Point: 4.0046

>AT284352 WP_056766693.1 NZ_CP128114:c1789852-1789412 [Bacillus safensis]
MGYESLKANQENSFYPVTENEIKEVEKELDLKFPKELVNFYMEVGYGFIKGSEFNNNRIMDPYSVRDFRLRVNDFEFYPD
IEIYDEFENNKLIFFEGSESALMSIELNEKNSSPVYYYDIQIATSLEEFLRKIEENDKYYLELLVD

Download         Length: 441 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References