Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2363306..2364284 Replicon chromosome
Accession NZ_CP128107
Organism Bacillus cereus strain D5_B_69

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag QRY07_RS12680 Protein ID WP_286119468.1
Coordinates 2363306..2364046 (+) Length 247 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID R8HWP4
Locus tag QRY07_RS12685 Protein ID WP_000588712.1
Coordinates 2364159..2364284 (+) Length 42 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRY07_RS12650 (QRY07_12650) 2358494..2359255 + 762 WP_002161793.1 ABC transporter ATP-binding protein -
QRY07_RS12655 (QRY07_12655) 2359362..2360072 + 711 WP_286119466.1 class I SAM-dependent methyltransferase -
QRY07_RS12660 (QRY07_12660) 2360192..2360605 + 414 WP_002200476.1 VOC family protein -
QRY07_RS12665 (QRY07_12665) 2360846..2361478 - 633 WP_283750177.1 type 1 glutamine amidotransferase family protein -
QRY07_RS12670 (QRY07_12670) 2361752..2362228 + 477 WP_002200474.1 MarR family winged helix-turn-helix transcriptional regulator -
QRY07_RS12675 (QRY07_12675) 2362382..2363119 + 738 WP_286119467.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
QRY07_RS12680 (QRY07_12680) 2363306..2364046 + 741 WP_286119468.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QRY07_RS12685 (QRY07_12685) 2364159..2364284 + 126 WP_000588712.1 hypothetical protein Antitoxin
QRY07_RS12690 (QRY07_12690) 2364360..2364536 + 177 WP_002200471.1 stage II sporulation protein SB -
QRY07_RS12695 (QRY07_12695) 2364714..2366183 + 1470 WP_286119469.1 beta-Ala-His dipeptidase -
QRY07_RS12700 (QRY07_12700) 2366266..2366634 + 369 Protein_2284 papain-like cysteine protease family protein -
QRY07_RS12705 (QRY07_12705) 2366662..2367264 + 603 WP_002200468.1 hypothetical protein -
QRY07_RS12710 (QRY07_12710) 2367676..2368857 + 1182 WP_286119470.1 agmatine deiminase family protein -
QRY07_RS12715 (QRY07_12715) 2368976..2369143 - 168 WP_255298773.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(10-244)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 247 a.a.        Molecular weight: 28437.09 Da        Isoelectric Point: 8.3034

>T284347 WP_286119468.1 NZ_CP128107:2363306-2364046 [Bacillus cereus]
MTISNIRIGLFILVIAFVVLVFFYWRNEELYEEKKQRIRKTWYGLFIISVTVYFMIKGVDLTLWKNLLMFTAMVIFVDIA
FILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAAFGTMEWHTEEEYTKNLNAFLDSYGEKIGAK
IVVFEAVKELNTNFRGIRSQFSSIVPLEHIEQLNEQKAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIH
HSYFSK

Download         Length: 741 bp

Antitoxin


Download         Length: 42 a.a.        Molecular weight: 4938.34 Da        Isoelectric Point: 3.9150

>AT284347 WP_000588712.1 NZ_CP128107:2364159-2364284 [Bacillus cereus]
VIKDYDNDFFKEDNEDTTDFSLIKGDTLQQVEELEEELKRK

Download         Length: 126 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A366GQT1

References