Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 71897..72522 Replicon plasmid pELP1.10
Accession NZ_CP127882
Organism Serratia marcescens strain ELP1.10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QRD25_RS24180 Protein ID WP_286094224.1
Coordinates 72124..72522 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QRD25_RS24175 Protein ID WP_286094223.1
Coordinates 71897..72124 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRD25_RS24175 (QRD25_24185) 71897..72124 + 228 WP_286094223.1 toxin-antitoxin system antitoxin VapB Antitoxin
QRD25_RS24180 (QRD25_24190) 72124..72522 + 399 WP_286094224.1 tRNA(fMet)-specific endonuclease VapC Toxin
QRD25_RS24185 (QRD25_24195) 72558..74753 - 2196 WP_286094225.1 type IV conjugative transfer system coupling protein TraD -
QRD25_RS24190 (QRD25_24200) 74743..74952 - 210 WP_033641525.1 hypothetical protein -
QRD25_RS24195 (QRD25_24205) 74955..75488 - 534 WP_286094226.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..129237 129237


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

SpoVT-AbrB domain

(7-51)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14712.98 Da        Isoelectric Point: 7.8046

>T284344 WP_286094224.1 NZ_CP127882:72124-72522 [Serratia marcescens]
MLKYLLDTNTCIFTIKNKPAHVRERFSLNTSRLCISSVTLMELIYGAEKSQAPERNLAVLEGFIARLDVLNYDAAAAAHS
GQIRAELSRQGLPIGPFDLMIAGHARSQGLIVVTNHTREFARVDGLRIEDWC

Download         Length: 399 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8439.50 Da        Isoelectric Point: 4.3867

>AT284344 WP_286094223.1 NZ_CP127882:71897-72124 [Serratia marcescens]
METTVFLSNRSQAVRLPKAVALPEDVKRVEVIAVGRTRIITPAGEGWDSWFDGEDVSADFMTSRDQPPMQEREAF

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References