Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4123876..4124545 Replicon chromosome
Accession NZ_CP127881
Organism Serratia marcescens strain ELP1.10

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QRD25_RS19660 Protein ID WP_286093572.1
Coordinates 4123876..4124298 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag QRD25_RS19665 Protein ID WP_004931679.1
Coordinates 4124279..4124545 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRD25_RS19640 (QRD25_19645) 4119767..4121500 - 1734 WP_015378966.1 single-stranded-DNA-specific exonuclease RecJ -
QRD25_RS19645 (QRD25_19650) 4121507..4122223 - 717 WP_004931688.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QRD25_RS19650 (QRD25_19655) 4122250..4123149 - 900 WP_004931685.1 site-specific tyrosine recombinase XerD -
QRD25_RS19655 (QRD25_19660) 4123256..4123774 + 519 WP_004931683.1 flavodoxin FldB -
QRD25_RS19660 (QRD25_19665) 4123876..4124298 - 423 WP_286093572.1 protein YgfX Toxin
QRD25_RS19665 (QRD25_19670) 4124279..4124545 - 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
QRD25_RS19670 (QRD25_19675) 4124866..4125858 + 993 WP_286093573.1 tRNA-modifying protein YgfZ -
QRD25_RS19675 (QRD25_19680) 4125897..4126394 - 498 WP_044030541.1 DUF2165 domain-containing protein -
QRD25_RS19680 (QRD25_19685) 4126545..4127219 - 675 WP_021505704.1 hemolysin III family protein -
QRD25_RS19685 (QRD25_19690) 4127403..4128011 + 609 WP_004931670.1 HD domain-containing protein -
QRD25_RS19690 (QRD25_19695) 4128049..4128975 - 927 WP_286093574.1 ribokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 4120538..4192799 72261


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16573.68 Da        Isoelectric Point: 10.8114

>T284343 WP_286093572.1 NZ_CP127881:c4124298-4123876 [Serratia marcescens]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLVSDCMSKEEWRHLRQLLLYPPAGDGEQD

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT284343 WP_004931679.1 NZ_CP127881:c4124545-4124279 [Serratia marcescens]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References