Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3758393..3759276 Replicon chromosome
Accession NZ_CP127872
Organism Pseudomonas asiatica strain RYYT.1b

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag QQ994_RS17030 Protein ID WP_286100121.1
Coordinates 3758393..3758830 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID F8G488
Locus tag QQ994_RS17035 Protein ID WP_013973163.1
Coordinates 3758827..3759276 (-) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ994_RS17010 (QQ994_17010) 3753605..3754669 + 1065 WP_286100119.1 TerC family protein -
QQ994_RS17015 (QQ994_17015) 3754740..3755969 - 1230 WP_013973159.1 acyl-CoA dehydrogenase -
QQ994_RS17020 (QQ994_17020) 3756110..3757036 + 927 WP_025339647.1 LysR family transcriptional regulator -
QQ994_RS17025 (QQ994_17025) 3757231..3758385 + 1155 WP_286100120.1 aminotransferase class V-fold PLP-dependent enzyme -
QQ994_RS17030 (QQ994_17030) 3758393..3758830 - 438 WP_286100121.1 RES family NAD+ phosphorylase Toxin
QQ994_RS17035 (QQ994_17035) 3758827..3759276 - 450 WP_013973163.1 DUF2384 domain-containing protein Antitoxin
QQ994_RS17040 (QQ994_17040) 3759426..3760079 - 654 WP_286100122.1 oxygen-insensitive NAD(P)H nitroreductase -
QQ994_RS17045 (QQ994_17045) 3760184..3761107 + 924 WP_286100123.1 LysR family transcriptional regulator -
QQ994_RS17050 (QQ994_17050) 3761155..3761985 + 831 WP_025339652.1 AraC family transcriptional regulator -
QQ994_RS17055 (QQ994_17055) 3762036..3762620 + 585 WP_274120604.1 LysE family translocator -
QQ994_RS17060 (QQ994_17060) 3762745..3763959 - 1215 WP_286100124.1 sugar transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-130)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15999.21 Da        Isoelectric Point: 4.8258

>T284316 WP_286100121.1 NZ_CP127872:c3758830-3758393 [Pseudomonas asiatica]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSAWLEVEDFTPDSRLF

Download         Length: 438 bp

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 17004.59 Da        Isoelectric Point: 6.3405

>AT284316 WP_013973163.1 NZ_CP127872:c3759276-3758827 [Pseudomonas asiatica]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Download         Length: 450 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F8G488

References