Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3758393..3759276 Replicon chromosome
Accession NZ_CP127872
Organism Pseudomonas asiatica strain RYYT.1b

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag QQ994_RS17030 Protein ID WP_286100121.1
Coordinates 3758393..3758830 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID F8G488
Locus tag QQ994_RS17035 Protein ID WP_013973163.1
Coordinates 3758827..3759276 (-) Length 150 a.a.

Genomic Context

QQ994_RS17010QQ994_RS17020QQ994_RS17025QQ994_RS17045QQ994_RS17050QQ994_RS17055QQ994_RS17015QQ994_RS17030QQ994_RS17035QQ994_RS17040QQ994_RS17060
Location: 3753605..3754669 (1065 bp)
Type: Others
Protein ID: WP_286100119.1
Location: 3756110..3757036 (927 bp)
Type: Others
Protein ID: WP_025339647.1
Location: 3757231..3758385 (1155 bp)
Type: Others
Protein ID: WP_286100120.1
Location: 3760184..3761107 (924 bp)
Type: Others
Protein ID: WP_286100123.1
Location: 3761155..3761985 (831 bp)
Type: Others
Protein ID: WP_025339652.1
Location: 3762036..3762620 (585 bp)
Type: Others
Protein ID: WP_274120604.1
Location: 3754740..3755969 (1230 bp)
Type: Others
Protein ID: WP_013973159.1
Location: 3758393..3758830 (438 bp)
Type: Toxin
Protein ID: WP_286100121.1
Location: 3758827..3759276 (450 bp)
Type: Antitoxin
Protein ID: WP_013973163.1
Location: 3759426..3760079 (654 bp)
Type: Others
Protein ID: WP_286100122.1
Location: 3762745..3763959 (1215 bp)
Type: Others
Protein ID: WP_286100124.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QQ994_RS17010 (QQ994_17010)3753605..3754669+1065WP_286100119.1TerC family protein-
QQ994_RS17015 (QQ994_17015)3754740..3755969-1230WP_013973159.1acyl-CoA dehydrogenase-
QQ994_RS17020 (QQ994_17020)3756110..3757036+927WP_025339647.1LysR family transcriptional regulator-
QQ994_RS17025 (QQ994_17025)3757231..3758385+1155WP_286100120.1aminotransferase class V-fold PLP-dependent enzyme-
QQ994_RS17030 (QQ994_17030)3758393..3758830-438WP_286100121.1RES family NAD+ phosphorylaseToxin
QQ994_RS17035 (QQ994_17035)3758827..3759276-450WP_013973163.1DUF2384 domain-containing proteinAntitoxin
QQ994_RS17040 (QQ994_17040)3759426..3760079-654WP_286100122.1oxygen-insensitive NAD(P)H nitroreductase-
QQ994_RS17045 (QQ994_17045)3760184..3761107+924WP_286100123.1LysR family transcriptional regulator-
QQ994_RS17050 (QQ994_17050)3761155..3761985+831WP_025339652.1AraC family transcriptional regulator-
QQ994_RS17055 (QQ994_17055)3762036..3762620+585WP_274120604.1LysE family translocator-
QQ994_RS17060 (QQ994_17060)3762745..3763959-1215WP_286100124.1sugar transporter-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-130)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15999.21 Da        Isoelectric Point: 4.8258

>T284316 WP_286100121.1 NZ_CP127872:c3758830-3758393 [Pseudomonas asiatica]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSAWLEVEDFTPDSRLF

Download         Length: 438 bp

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 17004.59 Da        Isoelectric Point: 6.3405

>AT284316 WP_013973163.1 NZ_CP127872:c3759276-3758827 [Pseudomonas asiatica]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Download         Length: 450 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBF8G488

References