Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2392595..2393111 Replicon chromosome
Accession NZ_CP127872
Organism Pseudomonas asiatica strain RYYT.1b

Toxin (Protein)


Gene name relE Uniprot ID F8G1E7
Locus tag QQ994_RS11050 Protein ID WP_003259987.1
Coordinates 2392830..2393111 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID F8G1E6
Locus tag QQ994_RS11045 Protein ID WP_013972043.1
Coordinates 2392595..2392840 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ994_RS11025 (QQ994_11025) 2387834..2388631 - 798 WP_025338593.1 SDR family oxidoreductase -
QQ994_RS11030 (QQ994_11030) 2388718..2389641 - 924 WP_286101644.1 LysR substrate-binding domain-containing protein -
QQ994_RS11035 (QQ994_11035) 2390021..2391214 + 1194 WP_025338595.1 MFS transporter -
QQ994_RS11040 (QQ994_11040) 2391245..2392351 + 1107 WP_085663447.1 alkene reductase -
QQ994_RS11045 (QQ994_11045) 2392595..2392840 + 246 WP_013972043.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QQ994_RS11050 (QQ994_11050) 2392830..2393111 + 282 WP_003259987.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QQ994_RS11055 (QQ994_11055) 2393192..2393587 - 396 WP_023662326.1 hypothetical protein -
QQ994_RS11060 (QQ994_11060) 2393676..2394584 - 909 WP_075044797.1 LysR family transcriptional regulator -
QQ994_RS11065 (QQ994_11065) 2394876..2396180 + 1305 WP_286101645.1 MFS transporter -
QQ994_RS11070 (QQ994_11070) 2396211..2397452 + 1242 WP_286101646.1 Zn-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-76)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10909.78 Da        Isoelectric Point: 10.7594

>T284315 WP_003259987.1 NZ_CP127872:2392830-2393111 [Pseudomonas asiatica]
MTYKLEFLPSALKEWGKLGHTVREQIKKKLAERLQSPKVQADALRDLPNHYKIKLKASGYRLVYRVEDERIVVVVVSVGK
RERSEVYRSAQKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8779.21 Da        Isoelectric Point: 4.3611

>AT284315 WP_013972043.1 NZ_CP127872:2392595-2392840 [Pseudomonas asiatica]
MQNIFADVAVSVSELKKNPSAVMTGAAGMPVAVLNHNRVMGYMVPAELYEAMMERLEDLELSELAKSRLGEKGVPVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB F8G1E7

Antitoxin

Source ID Structure
AlphaFold DB F8G1E6

References