Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 4577217..4577805 Replicon chromosome
Accession NZ_CP127871
Organism Pseudomonas kurunegalensis strain ANKC.G2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QQ992_RS20835 Protein ID WP_286110881.1
Coordinates 4577217..4577519 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag QQ992_RS20840 Protein ID WP_286110882.1
Coordinates 4577512..4577805 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ992_RS20810 (QQ992_20810) 4573217..4573345 - 129 WP_009683677.1 PA1414 family protein -
QQ992_RS20815 (QQ992_20815) 4573470..4574363 - 894 WP_286110879.1 LysR substrate-binding domain-containing protein -
QQ992_RS20820 (QQ992_20820) 4574470..4575636 + 1167 WP_286110880.1 MFS transporter -
QQ992_RS20825 (QQ992_20825) 4575633..4576559 - 927 WP_025753882.1 DMT family transporter -
QQ992_RS20830 (QQ992_20830) 4576666..4577061 - 396 WP_104834183.1 transcriptional regulator -
QQ992_RS20835 (QQ992_20835) 4577217..4577519 + 303 WP_286110881.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QQ992_RS20840 (QQ992_20840) 4577512..4577805 + 294 WP_286110882.1 putative addiction module antidote protein Antitoxin
QQ992_RS20845 (QQ992_20845) 4577895..4578167 + 273 WP_286110883.1 hypothetical protein -
QQ992_RS20850 (QQ992_20850) 4578336..4579697 - 1362 WP_286110884.1 DEAD/DEAH box helicase -
QQ992_RS20855 (QQ992_20855) 4579801..4581102 + 1302 WP_119369164.1 mechanosensitive ion channel family protein -
QQ992_RS20860 (QQ992_20860) 4581148..4582524 - 1377 WP_119369163.1 cytosine permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(6-94)

Antitoxin

Uncharacterized protein HI1420

(7-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11251.93 Da        Isoelectric Point: 10.6106

>T284314 WP_286110881.1 NZ_CP127871:4577217-4577519 [Pseudomonas kurunegalensis]
MKKIESSSFRHWVAGLRDDSARARIISRINRLLEGLPGDVSPVGYGISELRIHCGPGYRVYFHQAGTTIVILLCGGDKGS
QQRDIKAARQILRSWRMQND

Download         Length: 303 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10517.96 Da        Isoelectric Point: 4.7906

>AT284314 WP_286110882.1 NZ_CP127871:4577512-4577805 [Pseudomonas kurunegalensis]
MTETFSEFDPAEYLTTPEAIALFMTDALETGDASYVAKAVGVVARAKGMSELARETGLSREQLYRSFSEHGNPTLKSFLT
VMKALGIDMTARPHLAG

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References