Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 4181566..4182724 Replicon chromosome
Accession NZ_CP127871
Organism Pseudomonas kurunegalensis strain ANKC.G2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QQ992_RS19135 Protein ID WP_286110712.1
Coordinates 4182158..4182724 (+) Length 189 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QQ992_RS19130 Protein ID WP_286113973.1
Coordinates 4181566..4182093 (+) Length 176 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ992_RS19110 (QQ992_19110) 4176959..4178032 + 1074 WP_027608722.1 microcin C ABC transporter permease YejB -
QQ992_RS19115 (QQ992_19115) 4178034..4179053 + 1020 WP_016711616.1 ABC transporter permease -
QQ992_RS19120 (QQ992_19120) 4179055..4180668 + 1614 WP_286110710.1 ABC transporter ATP-binding protein -
QQ992_RS19125 (QQ992_19125) 4181190..4181453 + 264 WP_286110711.1 DUF3077 domain-containing protein -
QQ992_RS19130 (QQ992_19130) 4181566..4182093 + 528 WP_286113973.1 helix-turn-helix transcriptional regulator Antitoxin
QQ992_RS19135 (QQ992_19135) 4182158..4182724 + 567 WP_286110712.1 HD domain-containing protein Toxin
QQ992_RS19140 (QQ992_19140) 4183053..4185983 + 2931 WP_286110713.1 aminotransferase -
QQ992_RS19145 (QQ992_19145) 4186268..4186723 + 456 WP_286110714.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4161050..4185983 24933


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(9-147)

Antitoxin

Cro/C1-type helix-turn-helix domain

(1-51)


Sequences

Toxin        


Download         Length: 189 a.a.        Molecular weight: 20942.57 Da        Isoelectric Point: 4.6450

>T284312 WP_286110712.1 NZ_CP127871:4182158-4182724 [Pseudomonas kurunegalensis]
VSDQNLHGKLEFLRQAEKLKSVTRSAHTSTGRRESTAEHSWRLALLALVFEEDLGDVDICKVLKLCLVHDLGEALNGDVP
APEAQAMPDKGMGERQDLLAITSTLEPSMQDNIVALFDEYEAATSPEAKVVKALDKIETILQHTQGDNPPGFDYAFNLEY
GRRYTDAIPFLASLRRTLDDETRQRMTG

Download         Length: 567 bp

Antitoxin


Download         Length: 176 a.a.        Molecular weight: 19496.21 Da        Isoelectric Point: 6.9013

>AT284312 WP_286113973.1 NZ_CP127871:4181566-4182093 [Pseudomonas kurunegalensis]
MLRHWRMLNRVKQLHAAQMFGVCQSTVSRWESGIQDAEPEQRARIEALLKARLSSAADHALARLVSGSSQPVHLVCDLTH
RLLACSAPREAEFHVPVSELLGVSLWPFATEEIASQEQRLADIGWRQNLTSPALEFATGENDSALVPIQHSLCRWTRLTL
SDGSTARLVETLSHI

Download         Length: 528 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References