Detailed information of TA system TA284312

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/-
• Location: 4181566..4182724
• Replicon: chromosome
• Accession: NZ_CP127871
• Organism: Pseudomonas kurunegalensis strain ANKC.G2

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: QQ992_RS19135
• Protein ID: WP_286110712.1
• Coordinates: 4182158..4182724 (+)
• Length: 189 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: QQ992_RS19130
• Protein ID: WP_286113973.1
• Coordinates: 4181566..4182093 (+)
• Length: 176 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QQ992_RS19110 (QQ992_19110)	4176959..4178032	+	1074	WP_027608722.1	microcin C ABC transporter permease YejB	-
QQ992_RS19115 (QQ992_19115)	4178034..4179053	+	1020	WP_016711616.1	ABC transporter permease	-
QQ992_RS19120 (QQ992_19120)	4179055..4180668	+	1614	WP_286110710.1	ABC transporter ATP-binding protein	-
QQ992_RS19125 (QQ992_19125)	4181190..4181453	+	264	WP_286110711.1	DUF3077 domain-containing protein	-
QQ992_RS19130 (QQ992_19130)	4181566..4182093	+	528	WP_286113973.1	helix-turn-helix transcriptional regulator	Antitoxin
QQ992_RS19135 (QQ992_19135)	4182158..4182724	+	567	WP_286110712.1	HD domain-containing protein	Toxin
QQ992_RS19140 (QQ992_19140)	4183053..4185983	+	2931	WP_286110713.1	aminotransferase	-
QQ992_RS19145 (QQ992_19145)	4186268..4186723	+	456	WP_286110714.1	transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	4161050..4185983	24933

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• 5'-deoxynucleotidase YfbR/HDDC2 (9-147)

Antitoxin

• Cro/C1-type helix-turn-helix domain (1-51)

Sequences

Toxin

Protein

• Length: 189 a.a.
• Molecular weight: 20942.57 Da
• Isoelectric Point: 4.6450

>T284312 WP_286110712.1 NZ_CP127871:4182158-4182724 [Pseudomonas kurunegalensis]
VSDQNLHGKLEFLRQAEKLKSVTRSAHTSTGRRESTAEHSWRLALLALVFEEDLGDVDICKVLKLCLVHDLGEALNGDVP
APEAQAMPDKGMGERQDLLAITSTLEPSMQDNIVALFDEYEAATSPEAKVVKALDKIETILQHTQGDNPPGFDYAFNLEY
GRRYTDAIPFLASLRRTLDDETRQRMTG

Nucleotide

• Length: 567 bp

Antitoxin

Protein

• Length: 176 a.a.
• Molecular weight: 19496.21 Da
• Isoelectric Point: 6.9013

>AT284312 WP_286113973.1 NZ_CP127871:4181566-4182093 [Pseudomonas kurunegalensis]
MLRHWRMLNRVKQLHAAQMFGVCQSTVSRWESGIQDAEPEQRARIEALLKARLSSAADHALARLVSGSSQPVHLVCDLTH
RLLACSAPREAEFHVPVSELLGVSLWPFATEEIASQEQRLADIGWRQNLTSPALEFATGENDSALVPIQHSLCRWTRLTL
SDGSTARLVETLSHI

Nucleotide

• Length: 528 bp