Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 333546..334079 Replicon chromosome
Accession NZ_CP127871
Organism Pseudomonas kurunegalensis strain ANKC.G2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QQ992_RS01365 Protein ID WP_286112011.1
Coordinates 333546..333767 (+) Length 74 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QQ992_RS01370 Protein ID WP_119368535.1
Coordinates 333777..334079 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ992_RS01340 (QQ992_01340) 328597..329370 - 774 WP_003255746.1 ABC transporter ATP-binding protein -
QQ992_RS01345 (QQ992_01345) 330002..331387 + 1386 WP_019096869.1 GABA permease -
QQ992_RS01350 (QQ992_01350) 331569..332012 - 444 WP_286112008.1 hypothetical protein -
QQ992_RS01355 (QQ992_01355) 332235..332456 + 222 WP_286112009.1 hypothetical protein -
QQ992_RS01360 (QQ992_01360) 332497..333477 - 981 WP_286112010.1 polyphosphate kinase 2 -
QQ992_RS01365 (QQ992_01365) 333546..333767 + 222 WP_286112011.1 hypothetical protein Toxin
QQ992_RS01370 (QQ992_01370) 333777..334079 + 303 WP_119368535.1 putative addiction module antidote protein Antitoxin
QQ992_RS01380 (QQ992_01380) 334382..334654 - 273 WP_003255742.1 oxidative damage protection protein -
QQ992_RS01385 (QQ992_01385) 334651..335718 - 1068 WP_286112012.1 A/G-specific adenine glycosylase -
QQ992_RS01390 (QQ992_01390) 335715..337973 - 2259 WP_286112013.1 AsmA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(26-72)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-90)


Sequences

Toxin        


Download         Length: 74 a.a.        Molecular weight: 8205.67 Da        Isoelectric Point: 8.7011

>T284310 WP_286112011.1 NZ_CP127871:333546-333767 [Pseudomonas kurunegalensis]
MLVNCVPIYSLKQLQIGCSVNCGLHFPMRIDYGPGYRVYFVQRGYEVIILLAGDDKASQARDIKSALKLARDL

Download         Length: 222 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10707.37 Da        Isoelectric Point: 4.8307

>AT284310 WP_119368535.1 NZ_CP127871:333777-334079 [Pseudomonas kurunegalensis]
MTDIKLSKWDAADHLKTEEDMALYLEACLEENDPALLAAALGDIARARGMAQLARDTGLTREGLYKALSAEGNPSLATIM
KVMAALGVRLHAEVLPRSVG

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References