284308

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 1958515..1958985 Replicon chromosome
Accession NZ_CP127869
Organism Staphylococcus epidermidis strain NG02

Toxin (Protein)


Gene name TsaT Uniprot ID Q5HQS5
Locus tag QQ988_RS09245 Protein ID WP_001829569.1
Coordinates 1958797..1958985 (+) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID -
Locus tag QQ988_RS09240 Protein ID WP_074839211.1
Coordinates 1958515..1958772 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ988_RS09205 (QQ988_09205) 1953780..1954322 - 543 WP_002476477.1 nitroreductase -
QQ988_RS09210 (QQ988_09210) 1954403..1955119 - 717 WP_002493469.1 type I 3-dehydroquinate dehydratase -
QQ988_RS09215 (QQ988_09215) 1955280..1955702 + 423 WP_002457221.1 organic hydroperoxide resistance protein -
QQ988_RS09220 (QQ988_09220) 1956108..1956608 + 501 WP_002474267.1 GNAT family N-acetyltransferase -
QQ988_RS09225 (QQ988_09225) 1956878..1957465 - 588 WP_002493470.1 histidine phosphatase family protein -
QQ988_RS09230 (QQ988_09230) 1957678..1957914 + 237 WP_002457224.1 hypothetical protein -
QQ988_RS09235 (QQ988_09235) 1957906..1958109 - 204 WP_002438966.1 sterile alpha motif-like domain-containing protein -
QQ988_RS09240 (QQ988_09240) 1958515..1958772 + 258 WP_074839211.1 hypothetical protein Antitoxin
QQ988_RS09245 (QQ988_09245) 1958797..1958985 + 189 WP_001829569.1 hypothetical protein Toxin
QQ988_RS09250 (QQ988_09250) 1959175..1959729 + 555 WP_002493471.1 lipoprotein N-acylation protein LnsA -
QQ988_RS09255 (QQ988_09255) 1959789..1960022 - 234 WP_001829664.1 hypothetical protein -
QQ988_RS09260 (QQ988_09260) 1960307..1961053 + 747 WP_002493472.1 poly-gamma-glutamate hydrolase family protein -
QQ988_RS09265 (QQ988_09265) 1961151..1961435 + 285 WP_002493473.1 hypothetical protein -
QQ988_RS09270 (QQ988_09270) 1961460..1961684 + 225 WP_002493474.1 hypothetical protein -
QQ988_RS09275 (QQ988_09275) 1962306..1962506 - 201 WP_002493475.1 cold-shock protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7229.94 Da        Isoelectric Point: 9.7844

>T284308 WP_001829569.1 NZ_CP127869:1958797-1958985 [Staphylococcus epidermidis]
MSLHFQILLWLSILFIIAGTILLVTMLKTKKEERKESYLGFTVIFLIFGFAILIYTFIFGIL

Download         Length: 189 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10044.08 Da        Isoelectric Point: 4.5440

>AT284308 WP_074839211.1 NZ_CP127869:1958515-1958772 [Staphylococcus epidermidis]
MKLNKTNIFNLIFTILFFSFNILITYNANIDYKLWLIPGLAICGFALFSSLTLVIIYSDLFSEILFFINIILALYYIYPI
FYEFV

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0N0LUH8

Antitoxin

Source ID Structure

References