Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1877863..1878008 Replicon chromosome
Accession NZ_CP127839
Organism Klebsiella pneumoniae RYC492

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1877899..1878001 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1877863..1878008 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRF73_RS09125 (QRF73_09125) 1872993..1875053 + 2061 WP_004148850.1 oligopeptidase B -
QRF73_RS09130 (QRF73_09130) 1875057..1875716 - 660 WP_002911407.1 exodeoxyribonuclease X -
QRF73_RS09135 (QRF73_09135) 1875795..1876025 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QRF73_RS09140 (QRF73_09140) 1876138..1876512 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QRF73_RS09145 (QRF73_09145) 1876516..1877385 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
QRF73_RS09150 (QRF73_09150) 1877402..1877740 + 339 WP_002911404.1 YebY family protein -
- 1877863..1878008 - 146 - - Antitoxin
- 1877899..1878001 + 103 - - Toxin
QRF73_RS09155 (QRF73_09155) 1878376..1878519 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QRF73_RS09160 (QRF73_09160) 1878624..1879592 - 969 WP_014907334.1 VirK/YbjX family protein -
QRF73_RS09165 (QRF73_09165) 1879749..1880402 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
QRF73_RS09170 (QRF73_09170) 1880399..1880590 - 192 WP_002911395.1 YebW family protein -
QRF73_RS09175 (QRF73_09175) 1880688..1880927 - 240 WP_002911393.1 YebV family protein -
QRF73_RS09180 (QRF73_09180) 1881043..1882476 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T284261 NZ_CP127839:1877899-1878001 [Klebsiella pneumoniae RYC492]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT284261 NZ_CP127839:c1878008-1877863 [Klebsiella pneumoniae RYC492]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References