284253

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 7937..8853 Replicon chromosome
Accession NZ_CP127833
Organism Bacillus mojavensis strain KRS009

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag QLQ02_RS00035 Protein ID WP_268471127.1
Coordinates 7937..8683 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID A0A6H2JPH3
Locus tag QLQ02_RS00040 Protein ID WP_010333922.1
Coordinates 8683..8853 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ02_RS00015 (3259) 3259..4209 - 951 WP_229147973.1 ring-cleaving dioxygenase -
QLQ02_RS00020 (4604) 4604..5920 + 1317 WP_286058655.1 serine/threonine exchanger -
QLQ02_RS00025 (6196) 6196..6813 + 618 WP_010333926.1 DUF47 domain-containing protein -
QLQ02_RS00030 (6826) 6826..7827 + 1002 WP_010333925.1 inorganic phosphate transporter -
QLQ02_RS00035 (7937) 7937..8683 + 747 WP_268471127.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QLQ02_RS00040 (8683) 8683..8853 + 171 WP_010333922.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QLQ02_RS00045 (8938) 8938..9075 + 138 WP_128568473.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISC -
QLQ02_RS00050 (9112) 9112..10005 - 894 WP_168747522.1 N-acetylmuramoyl-L-alanine amidase -
QLQ02_RS00055 (10018) 10018..10281 - 264 WP_010333919.1 phage holin -
QLQ02_RS00060 (10293) 10293..10562 - 270 WP_044156228.1 hemolysin XhlA family protein -
QLQ02_RS00065 (10619) 10619..11458 - 840 WP_286058656.1 phage portal protein -
QLQ02_RS00070 (11502) 11502..11666 - 165 WP_286058657.1 XkdX family protein -
QLQ02_RS00075 (11663) 11663..11992 - 330 WP_286058658.1 XkdW family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29143.53 Da        Isoelectric Point: 4.5470

>T284253 WP_268471127.1 NZ_CP127833:7937-8683 [Bacillus mojavensis]
MLLFFQIMVWCTMAALGFYVYATWRFEAKVKEKMSAIRKTWYLLFVFGAMIYWTYDPSSLFTNWERYVIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLDRLKTYQYLLKNEPIHVYYGSIEAYAQGIDKLLKTYADKMNLTASL
CHYSTQSDKDRLTEHMEDPADVQTRLDRKDVYYDQYGKVVLIPFTIETQSYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6550.57 Da        Isoelectric Point: 10.7601

>AT284253 WP_010333922.1 NZ_CP127833:8683-8853 [Bacillus mojavensis]
MENAFQNGCHPQAKKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6H2JPH3

References