Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumA-relB/upstrm_HI1419-dnstrm_HI1420 |
Location | 280882..281504 | Replicon | chromosome |
Accession | NZ_CP127408 | ||
Organism | Stenotrophomonas sp. 59 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | QP552_RS01190 | Protein ID | WP_049431373.1 |
Coordinates | 281214..281504 (-) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | QP552_RS01185 | Protein ID | WP_111112518.1 |
Coordinates | 280882..281175 (-) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QP552_RS01165 | 276553..277443 | + | 891 | WP_099551527.1 | 3-hydroxyisobutyrate dehydrogenase | - |
QP552_RS01170 | 277674..278099 | - | 426 | WP_004153735.1 | organic hydroperoxide resistance protein | - |
QP552_RS01175 | 278211..279167 | - | 957 | WP_258394028.1 | cation transporter | - |
QP552_RS01180 | 279370..280824 | + | 1455 | WP_111112517.1 | SulP family inorganic anion transporter | - |
QP552_RS01185 | 280882..281175 | - | 294 | WP_111112518.1 | putative addiction module antidote protein | Antitoxin |
QP552_RS01190 | 281214..281504 | - | 291 | WP_049431373.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
QP552_RS01195 | 281650..283431 | - | 1782 | WP_286074745.1 | peptidoglycan-binding protein | - |
QP552_RS01200 | 283475..283894 | - | 420 | WP_258394029.1 | DUF1311 domain-containing protein | - |
QP552_RS01205 | 284116..285147 | + | 1032 | WP_286074748.1 | tRNA dihydrouridine(20/20a) synthase DusA | - |
QP552_RS01210 | 285361..285735 | + | 375 | WP_049431386.1 | hypothetical protein | - |
QP552_RS01215 | 285809..286492 | + | 684 | WP_004136763.1 | response regulator transcription factor | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 10850.47 Da Isoelectric Point: 11.8946
>T284250 WP_049431373.1 NZ_CP127408:c281504-281214 [Stenotrophomonas sp. 59]
MAILQATETFTRWLRGLNDSRARGVIVERLQRVARGLEGDVRSVGHGVSELRINHGPGYRVYFTRRGRSIVVLLHGGDKS
SQRRDIEKAVRLAELL
MAILQATETFTRWLRGLNDSRARGVIVERLQRVARGLEGDVRSVGHGVSELRINHGPGYRVYFTRRGRSIVVLLHGGDKS
SQRRDIEKAVRLAELL
Download Length: 291 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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