284250

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 280882..281504 Replicon chromosome
Accession NZ_CP127408
Organism Stenotrophomonas sp. 59

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QP552_RS01190 Protein ID WP_049431373.1
Coordinates 281214..281504 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QP552_RS01185 Protein ID WP_111112518.1
Coordinates 280882..281175 (-) Length 98 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP552_RS01165 276553..277443 + 891 WP_099551527.1 3-hydroxyisobutyrate dehydrogenase -
QP552_RS01170 277674..278099 - 426 WP_004153735.1 organic hydroperoxide resistance protein -
QP552_RS01175 278211..279167 - 957 WP_258394028.1 cation transporter -
QP552_RS01180 279370..280824 + 1455 WP_111112517.1 SulP family inorganic anion transporter -
QP552_RS01185 280882..281175 - 294 WP_111112518.1 putative addiction module antidote protein Antitoxin
QP552_RS01190 281214..281504 - 291 WP_049431373.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QP552_RS01195 281650..283431 - 1782 WP_286074745.1 peptidoglycan-binding protein -
QP552_RS01200 283475..283894 - 420 WP_258394029.1 DUF1311 domain-containing protein -
QP552_RS01205 284116..285147 + 1032 WP_286074748.1 tRNA dihydrouridine(20/20a) synthase DusA -
QP552_RS01210 285361..285735 + 375 WP_049431386.1 hypothetical protein -
QP552_RS01215 285809..286492 + 684 WP_004136763.1 response regulator transcription factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 10850.47 Da        Isoelectric Point: 11.8946

>T284250 WP_049431373.1 NZ_CP127408:c281504-281214 [Stenotrophomonas sp. 59]
MAILQATETFTRWLRGLNDSRARGVIVERLQRVARGLEGDVRSVGHGVSELRINHGPGYRVYFTRRGRSIVVLLHGGDKS
SQRRDIEKAVRLAELL

Download         Length: 291 bp


Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10075.54 Da        Isoelectric Point: 7.3163

>AT284250 WP_111112518.1 NZ_CP127408:c281175-280882 [Stenotrophomonas sp. 59]
MSKLKTIPFDPADYLADDVAIAAYLSEALAAGDAGHFQEALGTVARARGMGGVAEVSGLGRESLYKALRPGAHPRFDTVQ
RVLSALGVHLIVQAGKA

Download         Length: 294 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References