Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 3073357..3074889 Replicon chromosome
Accession NZ_CP127404
Organism Stenotrophomonas sp. As-6

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag QP436_RS13630 Protein ID WP_205407028.1
Coordinates 3073357..3074679 (-) Length 441 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag QP436_RS13635 Protein ID WP_223880281.1
Coordinates 3074683..3074889 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP436_RS13615 3068766..3070400 - 1635 WP_205405403.1 TldD/PmbA family protein -
QP436_RS13620 3070428..3072059 - 1632 WP_205405402.1 TldD/PmbA family protein -
QP436_RS13625 3072742..3073356 + 615 WP_205407029.1 DUF938 domain-containing protein -
QP436_RS13630 3073357..3074679 - 1323 WP_205407028.1 type II toxin-antitoxin system HipA family toxin Toxin
QP436_RS13635 3074683..3074889 - 207 WP_223880281.1 helix-turn-helix transcriptional regulator Antitoxin
QP436_RS13640 3075095..3078781 - 3687 WP_205407027.1 indolepyruvate ferredoxin oxidoreductase family protein -
QP436_RS13645 3078953..3079588 + 636 WP_180164639.1 tetratricopeptide repeat protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(4-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(2-53)


Sequences

Toxin        


Download         Length: 441 a.a.        Molecular weight: 48797.47 Da        Isoelectric Point: 6.6886

>T284247 WP_205407028.1 NZ_CP127404:c3074679-3073357 [Stenotrophomonas sp. As-6]
MGTLRVWMNGVEVALWDDARNRASRLSYLSQWIGSTQSRPLSLSLPLLPDGESHQGQVVNDYFDNLLPDNVTIRNRIRDR
FATRSSNTFDLLEAIGRDCVGAVQLLPHSRTPDAIQRITFEPLNDSGVAEVLRQVTTSALPGTSSSDDAFRISIAGAQEK
TGLLLHDGQWCIPTGSTPSTHIFKLPLGIVGNMRADMHQSVENEWLCMHLLAAFGIPVADTQMGRFEDQGALIVERFDRR
LAADRVWWLRLPQEDMCQVFGLPAARKYESDGGPGIVAIMDLLRQSEQPEDRATFFKTQILFWMLAATDGHAKNFSVHID
AGGRFRLTPVYDVLSVYPILGRGPNQLDPHNAQLAMAVEGKNRHRKLHLVRRRHWNETARACGVADGAEPWIEALIASVE
PAIEHVTRQLPSGFPSTVSEPVFKGLRAAATRLSSMAPDA

Download         Length: 1323 bp

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7671.70 Da        Isoelectric Point: 11.8979

>AT284247 WP_223880281.1 NZ_CP127404:c3074889-3074683 [Stenotrophomonas sp. As-6]
MRAFRRQAGLSQAQLAERLGISRQAVGALERDPASASFERLMRVWAVLGLEISLQQRSPRENTSTSEW

Download         Length: 207 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References