Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2764513..2765107 Replicon chromosome
Accession NZ_CP127390
Organism Propionimicrobium sp. PCR01-08-3

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QQ658_RS12835 Protein ID WP_286025230.1
Coordinates 2764805..2765107 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QQ658_RS12830 Protein ID WP_286025229.1
Coordinates 2764513..2764812 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ658_RS12810 (QQ658_12810) 2762035..2763042 + 1008 WP_286027116.1 dihydroorotate dehydrogenase-like protein -
QQ658_RS12815 (QQ658_12815) 2763189..2763458 + 270 WP_286025226.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
QQ658_RS12820 (QQ658_12820) 2763445..2764194 + 750 WP_286025227.1 hypothetical protein -
QQ658_RS12825 (QQ658_12825) 2764232..2764513 - 282 WP_286025228.1 hypothetical protein -
QQ658_RS12830 (QQ658_12830) 2764513..2764812 - 300 WP_286025229.1 putative addiction module antidote protein Antitoxin
QQ658_RS12835 (QQ658_12835) 2764805..2765107 - 303 WP_286025230.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QQ658_RS12840 (QQ658_12840) 2765182..2767542 - 2361 WP_286025231.1 heavy metal translocating P-type ATPase -
QQ658_RS12845 (QQ658_12845) 2767542..2767748 - 207 WP_286025232.1 heavy metal-associated domain-containing protein -
QQ658_RS12850 (QQ658_12850) 2767789..2768103 - 315 WP_286025233.1 metal-sensitive transcriptional regulator -
QQ658_RS12855 (QQ658_12855) 2768160..2768690 + 531 WP_286025234.1 hypothetical protein -
QQ658_RS12860 (QQ658_12860) 2768714..2769037 + 324 WP_286025235.1 putative quinol monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11449.01 Da        Isoelectric Point: 10.5000

>T284245 WP_286025230.1 NZ_CP127390:c2765107-2764805 [Propionimicrobium sp. PCR01-08-3]
MVEVVKSTTFDRWLTRLRDRQGAGRILARIDRLSAGNRGDAKSVGAGIWELRIDYGPGYRVYYLQRGSRLILLLCGGDKS
SQQRDIENAHRIAREWISNE

Download         Length: 303 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10363.50 Da        Isoelectric Point: 4.2108

>AT284245 WP_286025229.1 NZ_CP127390:c2764812-2764513 [Propionimicrobium sp. PCR01-08-3]
MNDSAEQFSSYDGADYLSSLGDAAAYLEATLEDSDDPALIANALGTIARSGNLSQLARRVGMSREGLYKALSADGNPSFA
TIMKVASALGLKLHFETVS

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References