Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-PHD
Location 2540738..2541423 Replicon chromosome
Accession NZ_CP127390
Organism Propionimicrobium sp. PCR01-08-3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QQ658_RS11770 Protein ID WP_286025033.1
Coordinates 2540738..2541166 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QQ658_RS11775 Protein ID WP_286025034.1
Coordinates 2541163..2541423 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ658_RS11750 (QQ658_11750) 2536928..2537923 - 996 WP_286025029.1 glycosyltransferase -
QQ658_RS11755 (QQ658_11755) 2537968..2538972 - 1005 WP_286025030.1 glycosyltransferase family 9 protein -
QQ658_RS11760 (QQ658_11760) 2538969..2539571 - 603 WP_286025031.1 HAD family hydrolase -
QQ658_RS11765 (QQ658_11765) 2539646..2540605 + 960 WP_286025032.1 glycosyltransferase family 9 protein -
QQ658_RS11770 (QQ658_11770) 2540738..2541166 - 429 WP_286025033.1 type II toxin-antitoxin system VapC family toxin Toxin
QQ658_RS11775 (QQ658_11775) 2541163..2541423 - 261 WP_286025034.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QQ658_RS11780 (QQ658_11780) 2541600..2544473 - 2874 WP_286025035.1 cation-translocating P-type ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(16-131)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-43)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15293.28 Da        Isoelectric Point: 4.5730

>T284241 WP_286025033.1 NZ_CP127390:c2541166-2540738 [Propionimicrobium sp. PCR01-08-3]
MSADSISSPDHGERGLLDTSVFIAQESGRRIDVSLLPDEGYVSVITLAELEAGVLAASDQTIRSRRLATLTRVSALVPLQ
VDATAAAHWARMRVQLAESGRRVNVNDLWIAAVALANGLAVYTQDHDYDPLAELGELRVITV

Download         Length: 429 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9427.62 Da        Isoelectric Point: 5.0623

>AT284241 WP_286025034.1 NZ_CP127390:c2541423-2541163 [Propionimicrobium sp. PCR01-08-3]
MTIIAARDLRNHTSDVLRRVSDGERITVAVRGRPSVELAPVRQARPEFFSRSELAELVLSFQSDPGLTHDLSVLAGETTD
DLGPLT

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References