Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 2462844..2463394 Replicon chromosome
Accession NZ_CP127390
Organism Propionimicrobium sp. PCR01-08-3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QQ658_RS11370 Protein ID WP_286024959.1
Coordinates 2462844..2463116 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QQ658_RS11375 Protein ID WP_286024960.1
Coordinates 2463113..2463394 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ658_RS11340 (QQ658_11340) 2458132..2460483 + 2352 WP_286024953.1 DEAD/DEAH box helicase -
QQ658_RS11345 (QQ658_11345) 2460532..2460906 - 375 WP_286024954.1 type II toxin-antitoxin system death-on-curing family toxin -
QQ658_RS11350 (QQ658_11350) 2460903..2461106 - 204 WP_286024955.1 hypothetical protein -
QQ658_RS11355 (QQ658_11355) 2461293..2461658 - 366 WP_286024956.1 flp pilus-assembly TadE/G-like family protein -
QQ658_RS11360 (QQ658_11360) 2461697..2462008 - 312 WP_286024957.1 TadE family type IV pilus minor pilin -
QQ658_RS11365 (QQ658_11365) 2462177..2462473 - 297 WP_286024958.1 DUF4244 domain-containing protein -
QQ658_RS11370 (QQ658_11370) 2462844..2463116 - 273 WP_286024959.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QQ658_RS11375 (QQ658_11375) 2463113..2463394 - 282 WP_286024960.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QQ658_RS11380 (QQ658_11380) 2463629..2464177 - 549 WP_286024961.1 type II secretion system F family protein -
QQ658_RS11385 (QQ658_11385) 2464411..2465043 - 633 WP_286024962.1 pilus assembly protein TadB -
QQ658_RS11390 (QQ658_11390) 2465220..2466554 - 1335 WP_286024963.1 TadA family conjugal transfer-associated ATPase -
QQ658_RS11395 (QQ658_11395) 2466561..2467604 - 1044 WP_286024964.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10473.13 Da        Isoelectric Point: 10.5455

>T284240 WP_286024959.1 NZ_CP127390:c2463116-2462844 [Propionimicrobium sp. PCR01-08-3]
VSQRYDVEFTRSARRALTKELPEKVAAAAFEFISGPLRENPYRVGKPLREPLAPLYSARRGEYRVLYLIIDERVVVQVVA
VVHRRDAYKR

Download         Length: 273 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10117.31 Da        Isoelectric Point: 4.2173

>AT284240 WP_286024960.1 NZ_CP127390:c2463394-2463113 [Propionimicrobium sp. PCR01-08-3]
MVTISLAAARANLSKIVESAMTTHERFEITRNGESAAMLLSMDDYDSLLETVDILSRPDEVDAVHEGLADVDAGRLESLD
EVHAAMISRGRQS

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References