Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpIK/MazF(toxin)
Location 2183391..2183959 Replicon chromosome
Accession NZ_CP127390
Organism Propionimicrobium sp. PCR01-08-3

Toxin (Protein)


Gene name chpK Uniprot ID -
Locus tag QQ658_RS09995 Protein ID WP_286024709.1
Coordinates 2183391..2183732 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name chpI Uniprot ID -
Locus tag QQ658_RS10000 Protein ID WP_286024710.1
Coordinates 2183726..2183959 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ658_RS09970 (QQ658_09970) 2178596..2179255 - 660 WP_286024704.1 mismatch-specific DNA-glycosylase -
QQ658_RS09975 (QQ658_09975) 2179473..2181290 - 1818 WP_286024705.1 BCCT family transporter -
QQ658_RS09980 (QQ658_09980) 2181533..2181889 + 357 WP_286024706.1 hypothetical protein -
QQ658_RS09985 (QQ658_09985) 2182084..2182770 - 687 WP_286024707.1 SDR family oxidoreductase -
QQ658_RS09990 (QQ658_09990) 2182805..2183359 - 555 WP_286024708.1 GNAT family N-acetyltransferase -
QQ658_RS09995 (QQ658_09995) 2183391..2183732 - 342 WP_286024709.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QQ658_RS10000 (QQ658_10000) 2183726..2183959 - 234 WP_286024710.1 hypothetical protein Antitoxin
QQ658_RS10005 (QQ658_10005) 2184033..2185106 - 1074 WP_286024711.1 redox-regulated ATPase YchF -
QQ658_RS10010 (QQ658_10010) 2185402..2185926 + 525 WP_286024712.1 DUF4190 domain-containing protein -
QQ658_RS10015 (QQ658_10015) 2186057..2187349 - 1293 WP_286024713.1 M18 family aminopeptidase -
QQ658_RS10020 (QQ658_10020) 2187533..2188666 - 1134 WP_286024714.1 zinc-binding dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12314.21 Da        Isoelectric Point: 6.9804

>T284237 WP_286024709.1 NZ_CP127390:c2183732-2183391 [Propionimicrobium sp. PCR01-08-3]
VVTRGEIWWVDFGDPIGSEPGYRRPALVVSSDRFNRSRIATVIVTALTSNLRLAVMPGNVELEKGEADLPKDCVVNVSQT
LVIDRSRLSQSVGTLSAHLMAKVDEGLRLVLAL

Download         Length: 342 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8486.31 Da        Isoelectric Point: 3.9251

>AT284237 WP_286024710.1 NZ_CP127390:c2183959-2183726 [Propionimicrobium sp. PCR01-08-3]
MKTAVSVPDEVFREADEVAARLGWSRSQLYARAVGEFLERQGDDPVTSALDALADELSDETPPSMGRTLIDSGSWEW

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References