Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-Axe/YoeB-RelB
Location 825982..826505 Replicon chromosome
Accession NZ_CP127390
Organism Propionimicrobium sp. PCR01-08-3

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QQ658_RS03885 Protein ID WP_286026359.1
Coordinates 826251..826505 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag QQ658_RS03880 Protein ID WP_286026358.1
Coordinates 825982..826254 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ658_RS03860 (QQ658_03860) 821055..822332 + 1278 WP_286026354.1 ATP-dependent Clp protease ATP-binding subunit ClpX -
QQ658_RS03865 (QQ658_03865) 822401..823846 + 1446 WP_286026355.1 threonine synthase -
QQ658_RS03870 (QQ658_03870) 824033..824881 + 849 WP_286026356.1 lipoyl(octanoyl) transferase LipB -
QQ658_RS03875 (QQ658_03875) 824897..825901 + 1005 WP_286026357.1 lipoyl synthase -
QQ658_RS03880 (QQ658_03880) 825982..826254 + 273 WP_286026358.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QQ658_RS03885 (QQ658_03885) 826251..826505 + 255 WP_286026359.1 Txe/YoeB family addiction module toxin Toxin
QQ658_RS03890 (QQ658_03890) 826639..829197 - 2559 WP_286027025.1 valine--tRNA ligase -
QQ658_RS03895 (QQ658_03895) 829341..830201 - 861 WP_286026360.1 thioredoxin domain-containing protein -
QQ658_RS03900 (QQ658_03900) 830198..830842 - 645 WP_286026361.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-76)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10023.35 Da        Isoelectric Point: 6.4581

>T284232 WP_286026359.1 NZ_CP127390:826251-826505 [Propionimicrobium sp. PCR01-08-3]
VNLSWTEDAWNDYLYWQEQDKKTLRRINKLISDTMRHPSEGIGKPEPLKWEMQGAWSRRIDTANRLIYVVLDDTVCILSA
KDHY

Download         Length: 255 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10233.52 Da        Isoelectric Point: 4.5397

>AT284232 WP_286026358.1 NZ_CP127390:825982-826254 [Propionimicrobium sp. PCR01-08-3]
MVTAVTYSNFRKSLKTFMRQVNEDADMLLVTNTDPVDNVVVMSAADYDSLMETVRIYQNPYLQDKVLRGLESVRHGHTTA
HELIDVDDPS

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References