Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 35084..35682 Replicon chromosome
Accession NZ_CP127390
Organism Propionimicrobium sp. PCR01-08-3

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QQ658_RS00160 Protein ID WP_286025673.1
Coordinates 35368..35682 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QQ658_RS00155 Protein ID WP_286025672.1
Coordinates 35084..35377 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ658_RS00125 (QQ658_00125) 30881..31327 + 447 WP_286025666.1 helix-turn-helix transcriptional regulator -
QQ658_RS00130 (QQ658_00130) 31324..31875 + 552 WP_286025667.1 hypothetical protein -
QQ658_RS00135 (QQ658_00135) 31835..33268 - 1434 WP_286025668.1 PH domain-containing protein -
QQ658_RS00140 (QQ658_00140) 33427..33966 - 540 WP_286025669.1 PH domain-containing protein -
QQ658_RS00145 (QQ658_00145) 33967..34476 - 510 WP_286025670.1 LiaF-related protein -
QQ658_RS00150 (QQ658_00150) 34513..35010 - 498 WP_286025671.1 thiol peroxidase -
QQ658_RS00155 (QQ658_00155) 35084..35377 - 294 WP_286025672.1 putative addiction module antidote protein Antitoxin
QQ658_RS00160 (QQ658_00160) 35368..35682 - 315 WP_286025673.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QQ658_RS00165 (QQ658_00165) 35827..36339 + 513 WP_286025674.1 hypothetical protein -
QQ658_RS00175 (QQ658_00175) 36478..37152 - 675 WP_286025675.1 type II toxin-antitoxin system PemK/MazF family toxin -
QQ658_RS00180 (QQ658_00180) 37152..38003 - 852 WP_286025676.1 hypothetical protein -
QQ658_RS00185 (QQ658_00185) 38287..38940 + 654 WP_286025677.1 HAD hydrolase-like protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-94)

Antitoxin

Uncharacterized protein HI1420

(8-96)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11992.96 Da        Isoelectric Point: 10.6779

>T284229 WP_286025673.1 NZ_CP127390:c35682-35368 [Propionimicrobium sp. PCR01-08-3]
MRILRTEVYERWFRRLKDAQGKARIDIALRRCTLVGSVVGDIKPVGDGVQEMRIHSGPGYRVYFLHRPNELMLLVIGGDK
SSQSRDIEKAKAIAKQLKEEGQWR

Download         Length: 315 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10331.66 Da        Isoelectric Point: 4.3184

>AT284229 WP_286025672.1 NZ_CP127390:c35377-35084 [Propionimicrobium sp. PCR01-08-3]
MALTIEAWDPSEHLETQDDVVAYLNAALEDGDPALLQAALGDIAKARGMSSIAREAGVGRESLYKSLRIDGNPSWQTITK
VLAALDIRLEAKAPANA

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References