Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3689277..3689814 Replicon chromosome
Accession NZ_CP127389
Organism Proteus sp. HZ0627

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QQS39_RS16865 Protein ID WP_099076302.1
Coordinates 3689277..3689570 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8I0X075
Locus tag QQS39_RS16870 Protein ID WP_023583073.1
Coordinates 3689560..3689814 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQS39_RS16845 (QQS39_16845) 3684888..3685415 + 528 WP_099076296.1 single-stranded DNA-binding protein SSB1 -
QQS39_RS16850 (QQS39_16850) 3685889..3686848 + 960 WP_285805007.1 XamI family restriction endonuclease -
QQS39_RS16855 (QQS39_16855) 3686851..3688413 + 1563 WP_285805008.1 N-6 DNA methylase -
QQS39_RS16860 (QQS39_16860) 3688700..3689230 + 531 WP_151436251.1 zinc uptake transcriptional repressor Zur -
QQS39_RS16865 (QQS39_16865) 3689277..3689570 - 294 WP_099076302.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QQS39_RS16870 (QQS39_16870) 3689560..3689814 - 255 WP_023583073.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QQS39_RS16875 (QQS39_16875) 3689968..3690579 - 612 WP_151436253.1 transcriptional repressor LexA -
QQS39_RS16880 (QQS39_16880) 3690707..3691078 - 372 WP_151436254.1 diacylglycerol kinase -
QQS39_RS16885 (QQS39_16885) 3691209..3693692 + 2484 WP_285805009.1 glycerol-3-phosphate 1-O-acyltransferase PlsB -
QQS39_RS16890 (QQS39_16890) 3693796..3694650 - 855 WP_151436256.1 4-hydroxybenzoate octaprenyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11424.51 Da        Isoelectric Point: 10.2910

>T284227 WP_099076302.1 NZ_CP127389:c3689570-3689277 [Proteus sp. HZ0627]
MIFNIEFDKRALKEWQKLDQSIKEQFKKKLKKLQENPYIESARLKGDLSGCYKIKLRASGFRLVYQIIDSEVVILVIAIG
KREESKAYSLAEMRIQK

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9841.29 Da        Isoelectric Point: 4.5748

>AT284227 WP_023583073.1 NZ_CP127389:c3689814-3689560 [Proteus sp. HZ0627]
MTTIQVRVDDELKKEAYQVFEKMNLSPSDAIRLFLRYVSENEKLPFSEVSVVVGEQDEDEDILAVVRERLKKPCKRIRVN
IDDL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References