Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2514810..2515549 Replicon chromosome
Accession NZ_CP127389
Organism Proteus sp. HZ0627

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag QQS39_RS11850 Protein ID WP_285804602.1
Coordinates 2515064..2515549 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag QQS39_RS11845 Protein ID WP_151435479.1
Coordinates 2514810..2515076 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQS39_RS11810 (QQS39_11810) 2510461..2510943 + 483 WP_006533151.1 flagellar basal body-associated protein FliL -
QQS39_RS11815 (QQS39_11815) 2510949..2511980 + 1032 WP_151435474.1 flagellar motor switch protein FliM -
QQS39_RS11820 (QQS39_11820) 2511973..2512383 + 411 WP_023581830.1 flagellar motor switch protein FliN -
QQS39_RS11825 (QQS39_11825) 2512387..2512833 + 447 WP_151435475.1 flagellar biosynthetic protein FliO -
QQS39_RS11830 (QQS39_11830) 2512833..2513603 + 771 WP_151435476.1 flagellar type III secretion system pore protein FliP -
QQS39_RS11835 (QQS39_11835) 2513619..2513888 + 270 WP_151435477.1 flagellar biosynthesis protein FliQ -
QQS39_RS11840 (QQS39_11840) 2513894..2514676 + 783 WP_196736676.1 flagellar biosynthetic protein FliR -
QQS39_RS11845 (QQS39_11845) 2514810..2515076 + 267 WP_151435479.1 DUF1778 domain-containing protein Antitoxin
QQS39_RS11850 (QQS39_11850) 2515064..2515549 + 486 WP_285804602.1 GNAT family N-acetyltransferase Toxin
QQS39_RS11855 (QQS39_11855) 2515638..2516582 - 945 WP_196571542.1 flagellar hook-associated protein FlgL -
QQS39_RS11860 (QQS39_11860) 2516610..2518250 - 1641 WP_285804603.1 flagellar hook-associated protein FlgK -
QQS39_RS11865 (QQS39_11865) 2518368..2519354 - 987 WP_151435483.1 flagellar assembly peptidoglycan hydrolase FlgJ -
QQS39_RS11870 (QQS39_11870) 2519354..2520460 - 1107 WP_151435484.1 flagellar basal body P-ring protein FlgI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(28-151)

Antitoxin

Vibrio phage ICP1, Orf50

(6-81)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17817.47 Da        Isoelectric Point: 8.9704

>T284225 WP_285804602.1 NZ_CP127389:2515064-2515549 [Proteus sp. HZ0627]
MGKVTAPEPLSSSHEVADFYSSEIVLDNWIKQRGFKNQLLGASRTFVVCKENSHYVVGYYSLATGSVNHTEAINAIRRNM
PDPIPVIILARLAVDISFHGKGLGADLLRDAVLRCYHVAENIGVKAIMVHSLTENAKQFYLHNGFKASSTQENTLFLALK
K

Download         Length: 486 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10127.62 Da        Isoelectric Point: 4.5256

>AT284225 WP_151435479.1 NZ_CP127389:2514810-2515076 [Proteus sp. HZ0627]
MKSDVQLNIRAKESQRALIDTAAEILHKSRTDFILETACQAAEDVILDRRTFNLNDAQYAEFIEIIDAPVDIDPALEKLL
MRKPLWEK

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References