Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2184308..2185107 Replicon chromosome
Accession NZ_CP127389
Organism Proteus sp. HZ0627

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag QQS39_RS10205 Protein ID WP_151435279.1
Coordinates 2184308..2184832 (-) Length 175 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag QQS39_RS10210 Protein ID WP_099075495.1
Coordinates 2184829..2185107 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQS39_RS10190 (QQS39_10190) 2180635..2181576 - 942 WP_285804457.1 glyoxylate/hydroxypyruvate reductase GhrA -
QQS39_RS10200 (QQS39_10200) 2182532..2184232 + 1701 WP_151435278.1 C4-dicarboxylic acid transporter DauA -
QQS39_RS10205 (QQS39_10205) 2184308..2184832 - 525 WP_151435279.1 GNAT family N-acetyltransferase Toxin
QQS39_RS10210 (QQS39_10210) 2184829..2185107 - 279 WP_099075495.1 DUF1778 domain-containing protein Antitoxin
QQS39_RS10215 (QQS39_10215) 2185260..2186189 - 930 WP_285804458.1 TIGR01212 family radical SAM protein -
QQS39_RS10220 (QQS39_10220) 2186198..2187052 - 855 WP_109372214.1 3-deoxy-8-phosphooctulonate synthase -
QQS39_RS10225 (QQS39_10225) 2187110..2187919 - 810 WP_265576330.1 invasion regulator SirB1 -
QQS39_RS10230 (QQS39_10230) 2187903..2188751 - 849 WP_285804459.1 peptide chain release factor N(5)-glutamine methyltransferase -
QQS39_RS10235 (QQS39_10235) 2188751..2189833 - 1083 WP_088495429.1 peptide chain release factor 1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(4-87)


Sequences

Toxin        


Download         Length: 175 a.a.        Molecular weight: 19224.17 Da        Isoelectric Point: 9.3652

>T284224 WP_151435279.1 NZ_CP127389:c2184832-2184308 [Proteus sp. HZ0627]
MTIPNWHEEAISKKHDRNTFNCGDAVLNQFLYRHARQNHENGSAKTYLAINTNNNIIIGYYSLCPASIEFERTPEVIARG
LARHDIPVFRLARLATDLSVQGKGLGGQLLLAAGKRCLAVASELGGVALLIDAKNERVANWYISYGAVPLLDSPLSLLIS
FKTIYTALRMANKI

Download         Length: 525 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10339.00 Da        Isoelectric Point: 6.3497

>AT284224 WP_099075495.1 NZ_CP127389:c2185107-2184829 [Proteus sp. HZ0627]
MAQTLVENSERVSIRITTEDKSLLVRAASLENTNLTEFVLRNIVPVARQIIENNERLKLSEKDTLRVMELLDNPPKPNAK
LLAAAFALPDKV

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References