Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 774182..774821 Replicon chromosome
Accession NZ_CP127389
Organism Proteus sp. HZ0627

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QQS39_RS03595 Protein ID WP_196569324.1
Coordinates 774182..774586 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QQS39_RS03600 Protein ID WP_099074198.1
Coordinates 774579..774821 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQS39_RS03570 (QQS39_03570) 770148..770618 + 471 WP_036932916.1 6,7-dimethyl-8-ribityllumazine synthase -
QQS39_RS03575 (QQS39_03575) 770647..771060 + 414 WP_006535124.1 transcription antitermination factor NusB -
QQS39_RS03580 (QQS39_03580) 771164..772147 + 984 WP_151434303.1 thiamine-phosphate kinase -
QQS39_RS03585 (QQS39_03585) 772210..773106 - 897 WP_285805397.1 hypothetical protein -
QQS39_RS03590 (QQS39_03590) 773407..773742 - 336 WP_109371746.1 zinc ribbon domain-containing protein YjdM -
QQS39_RS03595 (QQS39_03595) 774182..774586 - 405 WP_196569324.1 tRNA(fMet)-specific endonuclease VapC Toxin
QQS39_RS03600 (QQS39_03600) 774579..774821 - 243 WP_099074198.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QQS39_RS03605 (QQS39_03605) 774938..775936 - 999 WP_285805872.1 ribose operon transcriptional repressor RbsR -
QQS39_RS03610 (QQS39_03610) 775950..776876 - 927 WP_285805398.1 ribokinase -
QQS39_RS03615 (QQS39_03615) 776955..777845 - 891 WP_151434308.1 ribose ABC transporter substrate-binding protein RbsB -
QQS39_RS03620 (QQS39_03620) 777888..778853 - 966 WP_196735400.1 ribose ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15304.51 Da        Isoelectric Point: 7.5228

>T284221 WP_196569324.1 NZ_CP127389:c774586-774182 [Proteus sp. HZ0627]
MIKYLLDTNIVIFTIKRRPEFLLPKFNQHAEQLAISTITLAELIFGAEKSLNSTKNLATVNDFVSRLTVLSYDELAAFHY
GDIRATLEKQGKRIGDNDLHIAAHARSKGLIVVTNNTREFERVDGLRIEDWTHH

Download         Length: 405 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9378.43 Da        Isoelectric Point: 4.6028

>AT284221 WP_099074198.1 NZ_CP127389:c774821-774579 [Proteus sp. HZ0627]
MIQHGKVFMSNRTQNVRLPAETRFPDDVKEVFVRVKGKERIITPIQNAWDSFFLSDQSVTDDFLSERPDQVTSERESFDD

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References