284220

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 499162..500513 Replicon chromosome
Accession NZ_CP127389
Organism Proteus sp. HZ0627

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag QQS39_RS02420 Protein ID WP_285805317.1
Coordinates 499162..500106 (-) Length 315 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag QQS39_RS02425 Protein ID WP_285805318.1
Coordinates 500103..500513 (-) Length 137 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQS39_RS02390 (QQS39_02390) 494276..495163 - 888 WP_151434127.1 2OG-Fe dioxygenase family protein -
QQS39_RS02395 (QQS39_02395) 495342..496955 - 1614 WP_151434128.1 sigma 54-interacting transcriptional regulator -
QQS39_RS02400 (QQS39_02400) 497371..497928 + 558 WP_151434129.1 electron transport protein HydN -
QQS39_RS02405 (QQS39_02405) 498001..498342 + 342 WP_151434130.1 hydrogenase maturation nickel metallochaperone HypA -
QQS39_RS02410 (QQS39_02410) 498351..498641 + 291 WP_109374307.1 hydrogenase maturation factor HybG -
QQS39_RS02415 (QQS39_02415) 498774..499088 + 315 WP_151434131.1 quaternary ammonium compound efflux SMR transporter SugE -
QQS39_RS02420 (QQS39_02420) 499162..500106 - 945 WP_285805317.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
QQS39_RS02425 (QQS39_02425) 500103..500513 - 411 WP_285805318.1 DUF6088 family protein Antitoxin
QQS39_RS02430 (QQS39_02430) 500893..501252 - 360 WP_006535438.1 fumarate reductase subunit FrdD -
QQS39_RS02435 (QQS39_02435) 501267..501659 - 393 WP_151434132.1 fumarate reductase subunit FrdC -
QQS39_RS02440 (QQS39_02440) 501674..502411 - 738 WP_151434133.1 succinate dehydrogenase/fumarate reductase iron-sulfur subunit -
QQS39_RS02445 (QQS39_02445) 502404..504200 - 1797 WP_196569913.1 fumarate reductase (quinol) flavoprotein subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(32-301)

Antitoxin

Protein of unknown function DUF6088

(6-130)


Sequences

Toxin        


Download         Length: 315 a.a.        Molecular weight: 36586.74 Da        Isoelectric Point: 8.1191

>T284220 WP_285805317.1 NZ_CP127389:c500106-499162 [Proteus sp. HZ0627]
MIKLKNQFLEVSDALALGNPAIPEKDYWVVALLAQLATLNFDTHQIVFSGGTALAKSHVRIFRMSEDVDIKLIPTDVFNL
FSRDKRKAKRKALLKEIEDILTLQSSHFSIEEKIVRDEYRYVEYQLKYPQQFSQAPCLRPIIKLELIETIPLLQVEHRSI
QSLVAQLYRQSQEVGKFACVTVQSILVEKVISMLRRTMLVKRDPKRKDDPTLVRHIYDIYCINIDQQLDYKALIPLFRIV
LQEDVKRFGKQHLDFVIDPIKELQLGLTELESNPLYYQRFIDFVTPMVFTTEIPNFDTCFASFKSIAQSLMINN

Download         Length: 945 bp

Antitoxin


Download         Length: 137 a.a.        Molecular weight: 15352.61 Da        Isoelectric Point: 10.6956

>AT284220 WP_285805318.1 NZ_CP127389:c500513-500103 [Proteus sp. HZ0627]
MTAANQINQKLKRSRRYVFERKDFEDIASYDQIGRALNQLIKQGNLMKIGYGLYTKARENSLTGRLMPTNPGGTDAILRE
VLKMKGVDFEIDALSLQSLSGNSTQIPSSVRYSWDPKQFNRKLVIGNRVLSAPNSK

Download         Length: 411 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References