284216

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 11267..11817 Replicon plasmid pB
Accession NZ_CP127380
Organism Xanthomonas fragariae strain LMG 703

Toxin (Protein)


Gene name parE Uniprot ID A0A1Y6HCU7
Locus tag OW158_RS20240 Protein ID WP_002804295.1
Coordinates 11267..11551 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1Y6HDJ6
Locus tag OW158_RS20245 Protein ID WP_002804296.1
Coordinates 11539..11817 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OW158_RS20205 (OW158_20205) 6873..7274 - 402 WP_002804331.1 hypothetical protein -
OW158_RS20210 (OW158_20210) 7326..7769 + 444 WP_145954081.1 hypothetical protein -
OW158_RS20215 (OW158_20215) 7776..7940 + 165 WP_156775378.1 hypothetical protein -
OW158_RS20220 (OW158_20220) 8128..8703 + 576 WP_040762337.1 recombinase family protein -
OW158_RS20225 (OW158_20225) 8714..8980 + 267 WP_002804333.1 hypothetical protein -
OW158_RS20230 (OW158_20230) 9178..10830 + 1653 WP_231892771.1 AAA family ATPase -
OW158_RS20235 (OW158_20235) 10899..11081 + 183 WP_134656646.1 hypothetical protein -
OW158_RS20240 (OW158_20240) 11267..11551 - 285 WP_002804295.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OW158_RS20245 (OW158_20245) 11539..11817 - 279 WP_002804296.1 CopG family ribbon-helix-helix protein Antitoxin
OW158_RS20250 (OW158_20250) 12100..12789 + 690 WP_231895784.1 antitoxin VbhA family protein -
OW158_RS20255 (OW158_20255) 12831..13382 + 552 WP_088057164.1 recombinase family protein -
OW158_RS20260 (OW158_20260) 13485..14117 + 633 WP_088057159.1 ParA family protein -
OW158_RS20265 (OW158_20265) 14110..14472 + 363 WP_088057160.1 hypothetical protein -
OW158_RS20270 (OW158_20270) 14555..14878 + 324 WP_088057161.1 ParC family partition-associated protein -
OW158_RS20275 (OW158_20275) 15062..16474 + 1413 WP_108817190.1 replication protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..27159 27159
- inside IScluster/Tn - - 8089..13382 5293


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-93)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10801.49 Da        Isoelectric Point: 10.0858

>T284216 WP_002804295.1 NZ_CP127380:c11551-11267 [Xanthomonas fragariae]
VPHLIWTPPALADVQRLYRFLAPKDADAARRAVQAIRAQVKILAHQPRIGRPVEDMAPEFRDWLIDFGDSGYVARYRINE
NMVTILAVRHQKEA

Download         Length: 285 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10760.05 Da        Isoelectric Point: 5.1991

>AT284216 WP_002804296.1 NZ_CP127380:c11817-11539 [Xanthomonas fragariae]
MASPTSLKLDDELKGRVQHLAQTQRRTPHWIMREAIAQYVEREEKRETFKQDALRAWEDYQRTGLHLTLEETDAWLAKLE
AGEDAELPACHT

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6HCU7

Antitoxin

Source ID Structure
AlphaFold DB A0A1Y6HDJ6

References