Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 13236..13815 Replicon plasmid pA
Accession NZ_CP127379
Organism Xanthomonas fragariae strain LMG 703

Toxin (Protein)


Gene name relE Uniprot ID A0A1Y6HD38
Locus tag OW158_RS20045 Protein ID WP_002805372.1
Coordinates 13522..13815 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1Y6HUN4
Locus tag OW158_RS20040 Protein ID WP_002805369.1
Coordinates 13236..13535 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OW158_RS20015 (OW158_20015) 8824..10668 + 1845 WP_065975501.1 hypothetical protein -
OW158_RS20020 (OW158_20020) 10665..11288 + 624 WP_002805358.1 transglycosylase SLT domain-containing protein -
OW158_RS20025 (OW158_20025) 11330..11554 + 225 WP_002805360.1 DUF3717 domain-containing protein -
OW158_RS20030 (OW158_20030) 11715..12290 - 576 WP_065975506.1 recombinase family protein -
OW158_RS20035 (OW158_20035) 12332..13021 - 690 WP_065975502.1 antitoxin VbhA family protein -
OW158_RS20040 (OW158_20040) 13236..13535 + 300 WP_002805369.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OW158_RS20045 (OW158_20045) 13522..13815 + 294 WP_002805372.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OW158_RS20050 (OW158_20050) 13893..14069 + 177 WP_156775376.1 hypothetical protein -
OW158_RS20055 (OW158_20055) 14066..14290 - 225 WP_002805375.1 hypothetical protein -
OW158_RS20060 (OW158_20060) 14511..15263 + 753 WP_065975503.1 hypothetical protein -
OW158_RS20065 (OW158_20065) 15767..16366 - 600 WP_065975504.1 hypothetical protein -
OW158_RS20070 (OW158_20070) 17024..18043 - 1020 WP_052032118.1 relaxase/mobilization nuclease domain-containing protein -
OW158_RS20075 (OW158_20075) 18030..18581 - 552 WP_065975505.1 plasmid mobilization relaxosome protein MobC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..29233 29233


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-55)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10915.49 Da        Isoelectric Point: 5.1409

>T284215 WP_002805372.1 NZ_CP127379:13522-13815 [Xanthomonas fragariae]
VLVLEWRETARADLLAIVDYISDDNPDAAQRLKDDIEAKASMLPERPKLYRPGRVAGTREMVVRSNYVVVYAEDARAVSI
LRVLHAAQQWPPVTGVE

Download         Length: 294 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10717.25 Da        Isoelectric Point: 8.9086

>AT284215 WP_002805369.1 NZ_CP127379:13236-13535 [Xanthomonas fragariae]
MAAHTSMLHIRVDDALKAQAAETLANVGLTVSDAVRILLTRVAKEGGLPAGLTADPEAHDAWFRGKVQEALADTRPAVPH
RQVMDEAQALIDRKRRARS

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6HD38

Antitoxin

Source ID Structure
AlphaFold DB A0A1Y6HUN4

References