Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2069222..2069892 Replicon chromosome
Accession NZ_CP127378
Organism Xanthomonas fragariae strain LMG 703

Toxin (Protein)


Gene name vapC Uniprot ID A0A1Y6H9H7
Locus tag OW158_RS09680 Protein ID WP_002805728.1
Coordinates 2069473..2069892 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1Y6HLT7
Locus tag OW158_RS09675 Protein ID WP_002805732.1
Coordinates 2069222..2069476 (+) Length 85 a.a.

Genomic Context

OW158_RS09655OW158_RS09660OW158_RS09665OW158_RS09670OW158_RS09675OW158_RS09680OW158_RS09685OW158_RS09690OW158_RS09695OW158_RS09700OW158_RS09650
Location: 2065893..2066126 (234 bp)
Type: Others
Protein ID: WP_002805742.1
Location: 2066130..2067008 (879 bp)
Type: Others
Protein ID: WP_002805739.1
Location: 2066980..2067867 (888 bp)
Type: Others
Protein ID: WP_172404498.1
Location: 2068529..2068810 (282 bp)
Type: Others
Protein ID: WP_002805735.1
Location: 2069222..2069476 (255 bp)
Type: Antitoxin
Protein ID: WP_002805732.1
Location: 2069473..2069892 (420 bp)
Type: Toxin
Protein ID: WP_002805728.1
Location: 2070049..2070660 (612 bp)
Type: Others
Protein ID: Protein_1853
Location: 2070749..2070991 (243 bp)
Type: Others
Protein ID: Protein_1854
Location: 2071109..2072475 (1367 bp)
Type: Others
Protein ID: Protein_1855
Location: 2072498..2073403 (906 bp)
Type: Others
Protein ID: Protein_1856
Location: 2064807..2065802 (996 bp)
Type: Others
Protein ID: WP_231892738.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OW158_RS09650 (OW158_09650)2064807..2065802-996WP_231892738.1LuxR family transcriptional regulator-
OW158_RS09655 (OW158_09655)2065893..2066126+234WP_002805742.1hypothetical protein-
OW158_RS09660 (OW158_09660)2066130..2067008+879WP_002805739.1helicase RepA family protein-
OW158_RS09665 (OW158_09665)2066980..2067867+888WP_172404498.1replication protein C, IncQ-type-
OW158_RS09670 (OW158_09670)2068529..2068810+282WP_002805735.1TraK family protein-
OW158_RS09675 (OW158_09675)2069222..2069476+255WP_002805732.1Arc family DNA-binding proteinAntitoxin
OW158_RS09680 (OW158_09680)2069473..2069892+420WP_002805728.1type II toxin-antitoxin system VapC family toxinToxin
OW158_RS09685 (OW158_09685)2070049..2070660+612Protein_1853P-type conjugative transfer protein TrbJ-
OW158_RS09690 (OW158_09690)2070749..2070991+243Protein_1854transposase-
OW158_RS09695 (OW158_09695)2071109..2072475+1367Protein_1855IS5 family transposase-
OW158_RS09700 (OW158_09700)2072498..2073403+906Protein_1856IS3 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--2036507..207237935872
-flankIS/Tn--2063396..20647331337


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14879.07 Da        Isoelectric Point: 5.1890

>T284212 WP_002805728.1 NZ_CP127378:2069473-2069892 [Xanthomonas fragariae]
MIVLDTNVVSEAIKPEPNPAVRAWLNEQVAETLYLSSVTLAELLFGIGALPNGKRKKGLGEALDGLLELFGERVLMFDTE
AARHYAELAVKARTAGKGFPTPDGYIGAIAASKGFIVATRDTSPFEAAGLTVINPWNHQ

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9522.89 Da        Isoelectric Point: 5.7425

>AT284212 WP_002805732.1 NZ_CP127378:2069222-2069476 [Xanthomonas fragariae]
MAILTVRNVPDEVHRALRLRAAEHGRSTEAEVREILESAVKSEKRIRMGDALAELGRQVVLTNDDFAVLDQVRDKVPAEP
MRFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1Y6H9H7

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1Y6HLT7

References