Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2291191..2292181 Replicon chromosome
Accession NZ_CP127376
Organism Bacillus arachidis strain YX15

Toxin (Protein)


Gene name spoIISA Uniprot ID A0A2C2U8G0
Locus tag QRY57_RS13250 Protein ID WP_026590827.1
Coordinates 2291191..2291931 (+) Length 247 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag QRY57_RS13255 Protein ID WP_026590828.1
Coordinates 2292053..2292181 (+) Length 43 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRY57_RS13230 (QRY57_13235) 2287294..2287623 - 330 WP_026590823.1 DUF1232 domain-containing protein -
QRY57_RS13235 (QRY57_13240) 2288124..2289434 + 1311 WP_026590824.1 DEAD/DEAH box helicase -
QRY57_RS13240 (QRY57_13245) 2289606..2290082 + 477 WP_286017684.1 MarR family transcriptional regulator -
QRY57_RS13245 (QRY57_13250) 2290259..2290993 + 735 WP_286017685.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
QRY57_RS13250 (QRY57_13255) 2291191..2291931 + 741 WP_026590827.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QRY57_RS13255 (QRY57_13260) 2292053..2292181 + 129 WP_026590828.1 hypothetical protein Antitoxin
QRY57_RS13260 (QRY57_13265) 2292258..2292434 + 177 WP_286017686.1 stage II sporulation protein SB -
QRY57_RS13265 (QRY57_13270) 2292450..2292836 - 387 WP_170833630.1 GNAT family N-acetyltransferase -
QRY57_RS13270 (QRY57_13275) 2293026..2294492 + 1467 WP_286017687.1 aminoacyl-histidine dipeptidase -
QRY57_RS13275 (QRY57_13280) 2295377..2295628 + 252 WP_286017688.1 hypothetical protein -
QRY57_RS13280 (QRY57_13285) 2295831..2296556 + 726 WP_286017689.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(10-244)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 247 a.a.        Molecular weight: 28363.15 Da        Isoelectric Point: 8.6877

>T284211 WP_026590827.1 NZ_CP127376:2291191-2291931 [Bacillus arachidis]
MTVSNIRIGLFFLVLVFLFLIFFYWKNEELYEEKKQLIRKTWYGVFITSVTIYFMVKGIDLTLWKNILMFVAMVIFVDIA
FILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPVAFGTMEWQTETEYAKSLNVFLDTYGEKIGAK
IVVFVTANELNTNFRGIRSQFSITVPLEHIEQLNAQKAVQVENVGIIPAKIVKDVCIVIDGQKNNLQDRDFENVYNLTIH
HSYFSK

Download         Length: 741 bp

Antitoxin


Download         Length: 43 a.a.        Molecular weight: 4974.35 Da        Isoelectric Point: 3.8954

>AT284211 WP_026590828.1 NZ_CP127376:2292053-2292181 [Bacillus arachidis]
VEKEYSNEFFKEETEDTTDFSLIKGDTMQQVESLEEELKRNG

Download         Length: 129 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C2U8G0

Antitoxin

Source ID Structure

References