Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) omega-epsilon-zeta/-
Location 2416234..2417675 Replicon chromosome
Accession NZ_CP127362
Organism Paracidovorax citrulli strain KACC 17913

Toxin (Protein)


Gene name avrRxo1 Uniprot ID -
Locus tag QRO12_RS11465 Protein ID WP_286014905.1
Coordinates 2416545..2417675 (-) Length 377 a.a.

Antitoxin (Protein)


Gene name arc1 Uniprot ID A1TRP1
Locus tag QRO12_RS11460 Protein ID WP_011796139.1
Coordinates 2416234..2416530 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRO12_RS11450 (QRO12_11450) 2414414..2415211 + 798 WP_011796141.1 BMA_0021/BMA_0022 family TOMM bacteriocin -
QRO12_RS11455 (QRO12_11455) 2415221..2416075 + 855 WP_232521745.1 class I SAM-dependent methyltransferase -
QRO12_RS11460 (QRO12_11460) 2416234..2416530 - 297 WP_011796139.1 hypothetical protein Antitoxin
QRO12_RS11465 (QRO12_11465) 2416545..2417675 - 1131 WP_286014905.1 XopAJ/AvrRxo1 family type III secretion system effector zeta toxin Toxin
QRO12_RS11470 (QRO12_11470) 2417566..2417835 + 270 WP_225981105.1 hypothetical protein -
QRO12_RS11475 (QRO12_11475) 2418049..2420253 + 2205 WP_041828059.1 TOMM precursor leader peptide-binding protein -
QRO12_RS11480 (QRO12_11480) 2420318..2421241 + 924 WP_228193810.1 FHA domain-containing protein -
QRO12_RS11485 (QRO12_11485) 2421407..2421535 + 129 WP_258868820.1 hypothetical protein -
QRO12_RS11490 (QRO12_11490) 2421557..2421895 + 339 WP_011796135.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(107-246)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 377 a.a.        Molecular weight: 40142.32 Da        Isoelectric Point: 7.0221

>T284206 WP_286014905.1 NZ_CP127362:c2417675-2416545 [Paracidovorax citrulli]
VHALPAGFPAPSQRSRSSSPSRVRASLPAKVPETSGNRPAIRLPAAPRGSDEIFGLGELPPPGQSRWDYLAHPQNWRPER
RQLHDRLIGDAKTAAQDFAEVIERGGHPPTLFALRGNTAAGKTRMATQTIPVLANALKESGGAGCINPDIFKRSLAETPE
GAKLTSAQVHAESCILADRLEDELRLQKTASGAAISMLVDKRLAGAHEIDAYIKLAQETGRKIELCDIDAPLEQSLMGVL
QRKPEGDAPRPPYVAVANGFSAVRGHRLDVIDKFLSNPTLGSYHLFGTTGNGSKAMVASVVNGELSIHDPQLYEAITDPQ
GARAGDSGDQIIDAALIDRLTKGIDDPARAMDARTALERYAGMTWSDALAAHSSLT

Download         Length: 1131 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11106.62 Da        Isoelectric Point: 6.9795

>AT284206 WP_011796139.1 NZ_CP127362:c2416530-2416234 [Paracidovorax citrulli]
MTGLKGADALDFHKKLKERNAALRNAELNAAKELADKNGKEPFDLVKLERLCDTSQAGRLVEGTERQAMYEYMYYVEYKN
VGTLQDFARVVTTLASWS

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A1TRP1

References