284116

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) ypjF-yeeU/CbtA-CbeA
Location 2449571..2450271 Replicon chromosome
Accession NZ_CP127306
Organism Escherichia coli strain C51

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag QRM70_RS11900 Protein ID WP_021571969.1
Coordinates 2449948..2450271 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag QRM70_RS11895 Protein ID WP_021571970.1
Coordinates 2449571..2449927 (+) Length 119 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRM70_RS11860 (2445608) 2445608..2446324 + 717 WP_021571976.1 WYL domain-containing protein -
QRM70_RS11865 (2446360) 2446360..2446812 + 453 WP_021571975.1 hypothetical protein -
QRM70_RS11870 (2446884) 2446884..2447357 + 474 WP_021554938.1 hypothetical protein -
QRM70_RS11875 (2447477) 2447477..2448298 + 822 WP_021571974.1 DUF932 domain-containing protein -
QRM70_RS11880 (2448329) 2448329..2448772 + 444 WP_021571973.1 antirestriction protein -
QRM70_RS11885 (2448785) 2448785..2449327 + 543 WP_021571972.1 DNA repair protein RadC -
QRM70_RS11890 (2449324) 2449324..2449545 + 222 WP_021571971.1 DUF987 family protein -
QRM70_RS11895 (2449571) 2449571..2449927 + 357 WP_021571970.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
QRM70_RS11900 (2449948) 2449948..2450271 + 324 WP_021571969.1 TA system toxin CbtA family protein Toxin
QRM70_RS11905 (2450713) 2450713..2452323 + 1611 WP_000676929.1 glycoside hydrolase family 15 protein -
QRM70_RS11910 (2452415) 2452415..2453402 + 988 Protein_2295 YscQ/HrcQ family type III secretion apparatus protein -
QRM70_RS11915 (2453392) 2453392..2454057 + 666 Protein_2296 EscR/YscR/HrcR family type III secretion system export apparatus protein -
QRM70_RS11920 (2454067) 2454067..2454327 + 261 WP_000341004.1 EscS/YscS/HrcS family type III secretion system export apparatus protein -
QRM70_RS11925 (2454329) 2454329..2455096 + 768 WP_097555019.1 type III secretion system export apparatus subunit SctT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-107)

Antitoxin

(17-117)


Sequences


Toxin        


Download         Length: 108 a.a.        Molecular weight: 12404.50 Da        Isoelectric Point: 7.8568

>T284116 WP_021571969.1 NZ_CP127306:2449948-2450271 [Escherichia coli]
MKFLPATNMRAAKPCLPPVTIWQMLLSRLLEQHYGLSLNDTPFCDATVIQEHIDAGITLANAINFLVEKYELVRIDRRGF
SWQEQTPYLTIIDIMRARRDLGIMNRN

Download         Length: 324 bp


Antitoxin


Download         Length: 119 a.a.        Molecular weight: 13206.03 Da        Isoelectric Point: 6.7341

>AT284116 WP_021571970.1 NZ_CP127306:2449571-2449927 [Escherichia coli]
MNNHSESGAIPENLPCKQWGLKSTITPCFGARLVQEGYRLHFLADRAGFNGSFSDEHVLRLDQAFPLILKQLELLLTSGE
LSPRHQHCITLYHNGLTCEADTLGSCGYVYIAIYPTQR

Download         Length: 357 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References