284108

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 863432..864027 Replicon chromosome
Accession NZ_CP127306
Organism Escherichia coli strain C51

Toxin (Protein)


Gene name chpB Uniprot ID U9Y4M4
Locus tag QRM70_RS04255 Protein ID WP_000239579.1
Coordinates 863432..863782 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID U9Y2K1
Locus tag QRM70_RS04260 Protein ID WP_001223208.1
Coordinates 863776..864027 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRM70_RS04235 (858708) 858708..859730 - 1023 WP_001339490.1 ABC transporter permease -
QRM70_RS04240 (859744) 859744..861246 - 1503 WP_021548597.1 sugar ABC transporter ATP-binding protein -
QRM70_RS04245 (861556) 861556..862512 - 957 WP_000265933.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
QRM70_RS04250 (862822) 862822..863352 + 531 WP_000055072.1 inorganic diphosphatase -
QRM70_RS04255 (863432) 863432..863782 - 351 WP_000239579.1 endoribonuclease toxin ChpB Toxin
QRM70_RS04260 (863776) 863776..864027 - 252 WP_001223208.1 type II toxin-antitoxin system antitoxin ChpS Antitoxin
QRM70_RS04265 (864240) 864240..864581 - 342 WP_001219160.1 gamma-glutamylcyclotransferase -
QRM70_RS04270 (864584) 864584..868363 - 3780 WP_000060901.1 autotransporter assembly complex protein TamB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12511.45 Da        Isoelectric Point: 5.6219

>T284108 WP_000239579.1 NZ_CP127306:c863782-863432 [Escherichia coli]
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLV
NQVRMMDLRARLAKRIGLAADEVVEEALLRLQAVVE

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9271.58 Da        Isoelectric Point: 4.4201

>AT284108 WP_001223208.1 NZ_CP127306:c864027-863776 [Escherichia coli]
MRITIKRWGNSAGMVIPNIVMKELNLQPGQSVEAQVSNNQLILTPISRRYSLDELLAQCDMNAAELSEQDVWGKSTPAGD
EIW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0Y8A8

Antitoxin

Source ID Structure
AlphaFold DB A0A7U9LQ26

References