Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 1649887..1650812 Replicon chromosome
Accession NZ_CP127303
Organism Escherichia coli strain APEC37

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag QRM68_RS09435 Protein ID WP_014640052.1
Coordinates 1650426..1650812 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag QRM68_RS09430 Protein ID WP_024174200.1
Coordinates 1649887..1650396 (+) Length 170 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRM68_RS09400 (1645556) 1645556..1646881 + 1326 WP_001351388.1 MATE family efflux transporter DinF -
QRM68_RS09405 (1646997) 1646997..1647206 + 210 WP_001030593.1 CsbD family protein -
QRM68_RS09410 (1647248) 1647248..1647763 - 516 WP_001295691.1 zinc uptake transcriptional repressor Zur -
QRM68_RS09415 (1648082) 1648082..1648363 + 282 Protein_1545 DUF2713 domain-containing protein -
QRM68_RS09420 (1648358) 1648358..1649103 + 746 Protein_1546 DUF2713 family protein -
QRM68_RS09425 (1649466) 1649466..1649570 + 105 Protein_1547 tRNA-dihydrouridine synthase -
QRM68_RS09430 (1649887) 1649887..1650396 + 510 WP_024174200.1 Panacea domain-containing protein Antitoxin
QRM68_RS09435 (1650426) 1650426..1650812 + 387 WP_014640052.1 hypothetical protein Toxin
QRM68_RS09440 (1650852) 1650852..1651025 + 174 WP_000390072.1 hypothetical protein -
QRM68_RS09445 (1651073) 1651073..1651354 - 282 WP_001093916.1 pyocin activator PrtN family protein -
QRM68_RS09450 (1651391) 1651391..1652173 - 783 WP_047654657.1 hypothetical protein -
QRM68_RS09455 (1652362) 1652362..1653186 - 825 WP_000081311.1 DUF2303 family protein -
QRM68_RS09460 (1653252) 1653252..1653614 - 363 WP_097472974.1 protein YfdP -
QRM68_RS09465 (1653629) 1653629..1653939 - 311 Protein_1555 hypothetical protein -
QRM68_RS09470 (1654215) 1654215..1654490 - 276 WP_001514782.1 hypothetical protein -
QRM68_RS09475 (1654953) 1654953..1655627 - 675 WP_000859461.1 LexA family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1644875..1689960 45085


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(6-116)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14465.40 Da        Isoelectric Point: 5.4833

>T284093 WP_014640052.1 NZ_CP127303:1650426-1650812 [Escherichia coli]
VLAPTGPCNHLHVICNDPVYYPVNDCYCVLVVNISSIKDGVPHDPSCVLNSGDHRFIKHPSYVVYAEAIIWRVDNMVRKQ
RSGEISVHDDMPEATFNRILDGFDISDEVTPKNLKFKNKYCVSSIDDE

Download         Length: 387 bp

Antitoxin


Download         Length: 170 a.a.        Molecular weight: 19559.39 Da        Isoelectric Point: 5.3338

>AT284093 WP_024174200.1 NZ_CP127303:1649887-1650396 [Escherichia coli]
MAYLKLMKLLYLSNRKSILKHGRMIGEDSLYSMKFGPVMSNTLNLIRGKAEGIGDYWYNLIETNGHDVLLRSDPREMDAD
EVFDELSRADIRILDEIYSLYGHMNRFDLANMTHLESVCPEWHNPGNSRKPIDLKEMLISEGKSEDEANRIIGKMEESQK
LKEFSLQLS

Download         Length: 510 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References