Detailed information of TA system TA028409

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3738023..3738676
• Replicon: chromosome
• Accession: NC_018706
• Organism: Acinetobacter baumannii TYTH-1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: M3Q_RS17665
• Protein ID: WP_000607077.1
• Coordinates: 3738023..3738412 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: M3Q_RS17670
• Protein ID: WP_001288210.1
• Coordinates: 3738419..3738676 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M3Q_RS17650	3733141..3735336	-	2196	WP_001158906.1	TRAP transporter large permease subunit	-
M3Q_RS17655	3735524..3736090	-	567	WP_000651538.1	rhombosortase	-
M3Q_RS17660	3736168..3737253	-	1086	WP_000049106.1	hypothetical protein	-
M3Q_RS17665	3738023..3738412	-	390	WP_000607077.1	membrane protein	Toxin
M3Q_RS17670	3738419..3738676	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
M3Q_RS17675	3738864..3740036	+	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
M3Q_RS17680	3740085..3741575	-	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
M3Q_RS17685	3741757..3742047	-	291	WP_015011256.1	50S ribosomal protein L17	-
M3Q_RS17690	3742122..3743129	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T28409 WP_000607077.1 NC_018706:c3738412-3738023 [Acinetobacter baumannii TYTH-1]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T28409 NC_018706:c3738412-3738023 [Acinetobacter baumannii TYTH-1]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT28409 WP_001288210.1 NC_018706:c3738676-3738419 [Acinetobacter baumannii TYTH-1]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT28409 NC_018706:c3738676-3738419 [Acinetobacter baumannii TYTH-1]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7