Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-YafN |
| Location | 165714..166249 | Replicon | plasmid pAPEC3701 |
| Accession | NZ_CP127301 | ||
| Organism | Escherichia coli strain APEC37 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | V0VJJ7 |
| Locus tag | QRM68_RS00920 | Protein ID | WP_000222760.1 |
| Coordinates | 165962..166249 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | V0VIP2 |
| Locus tag | QRM68_RS00915 | Protein ID | WP_001132900.1 |
| Coordinates | 165714..165965 (+) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QRM68_RS00870 (160843) | 160843..161403 | + | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| QRM68_RS00875 (161539) | 161539..161751 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| QRM68_RS00880 (161997) | 161997..162071 | + | 75 | Protein_175 | endonuclease | - |
| - (162325) | 162325..162386 | - | 62 | NuclAT_1 | - | - |
| - (162325) | 162325..162386 | - | 62 | NuclAT_1 | - | - |
| - (162325) | 162325..162386 | - | 62 | NuclAT_1 | - | - |
| - (162325) | 162325..162386 | - | 62 | NuclAT_1 | - | - |
| QRM68_RS00885 (162430) | 162430..162579 | + | 150 | WP_001312851.1 | Hok/Gef family protein | - |
| QRM68_RS00890 (162863) | 162863..163120 | + | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| QRM68_RS00895 (163137) | 163137..163388 | - | 252 | WP_223195197.1 | replication protein RepA | - |
| QRM68_RS00900 (163379) | 163379..163426 | + | 48 | WP_229471593.1 | hypothetical protein | - |
| QRM68_RS00905 (163419) | 163419..163901 | + | 483 | WP_001273588.1 | hypothetical protein | - |
| QRM68_RS00910 (163894) | 163894..164751 | + | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| QRM68_RS00915 (165714) | 165714..165965 | + | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| QRM68_RS00920 (165962) | 165962..166249 | + | 288 | WP_000222760.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| QRM68_RS00925 (166353) | 166353..166673 | + | 321 | Protein_184 | serine acetyltransferase | - |
| QRM68_RS00930 (166689) | 166689..167036 | - | 348 | Protein_185 | IS1-like element IS1A family transposase | - |
| QRM68_RS00935 (167125) | 167125..168147 | + | 1023 | WP_000255956.1 | IS21-like element IS100 family transposase | - |
| QRM68_RS00940 (168144) | 168144..168926 | + | 783 | WP_001442137.1 | IS21-like element IS100kyp family helper ATPase IstB | - |
| QRM68_RS00945 (168981) | 168981..169345 | - | 365 | Protein_188 | IS1 family transposase | - |
| QRM68_RS00950 (169445) | 169445..170648 | + | 1204 | Protein_189 | ISL3 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Conjugative plasmid | sitABCD | vat / vat / iroN / iroN / iroE / iroD / iroC / iroB / iucA / iucB / iucB / iucC / iucC / iucD / iutA | 1..192709 | 192709 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|