Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PumA-relB/upstrm_HI1419-dnstrm_HI1420 |
| Location | 3948747..3949345 | Replicon | chromosome |
| Accession | NC_018691 | ||
| Organism | Alcanivorax dieselolei B5 | ||
Toxin (Protein)
| Gene name | PumA | Uniprot ID | - |
| Locus tag | B5T_RS17535 | Protein ID | WP_014995878.1 |
| Coordinates | 3948747..3949049 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | B5T_RS23530 | Protein ID | WP_014995879.1 |
| Coordinates | 3949046..3949345 (+) | Length | 100 a.a. |
Genomic Context
Location: 3947350..3947604 (255 bp)
Type: Others
Protein ID: WP_041717714.1
Type: Others
Protein ID: WP_041717714.1
Location: 3947601..3947945 (345 bp)
Type: Others
Protein ID: WP_014995875.1
Type: Others
Protein ID: WP_014995875.1
Location: 3948747..3949049 (303 bp)
Type: Toxin
Protein ID: WP_014995878.1
Type: Toxin
Protein ID: WP_014995878.1
Location: 3949046..3949345 (300 bp)
Type: Antitoxin
Protein ID: WP_014995879.1
Type: Antitoxin
Protein ID: WP_014995879.1
Location: 3945084..3946058 (975 bp)
Type: Others
Protein ID: WP_041717100.1
Type: Others
Protein ID: WP_041717100.1
Location: 3946251..3947228 (978 bp)
Type: Others
Protein ID: WP_014995873.1
Type: Others
Protein ID: WP_014995873.1
Location: 3947993..3948316 (324 bp)
Type: Others
Protein ID: WP_014995876.1
Type: Others
Protein ID: WP_014995876.1
Location: 3949319..3949756 (438 bp)
Type: Others
Protein ID: WP_202803017.1
Type: Others
Protein ID: WP_202803017.1
Location: 3950047..3951897 (1851 bp)
Type: Others
Protein ID: WP_014995881.1
Type: Others
Protein ID: WP_014995881.1
Location: 3952037..3953269 (1233 bp)
Type: Others
Protein ID: WP_041717716.1
Type: Others
Protein ID: WP_041717716.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| B5T_RS17505 | 3945084..3946058 | - | 975 | WP_041717100.1 | type I-F CRISPR-associated endonuclease Cas1 | - |
| B5T_RS17510 | 3946251..3947228 | - | 978 | WP_014995873.1 | YafY family transcriptional regulator | - |
| B5T_RS17515 | 3947350..3947604 | + | 255 | WP_041717714.1 | type II toxin-antitoxin system HicA family toxin | - |
| B5T_RS17520 | 3947601..3947945 | + | 345 | WP_014995875.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| B5T_RS17525 | 3947993..3948316 | - | 324 | WP_014995876.1 | hypothetical protein | - |
| B5T_RS17535 | 3948747..3949049 | + | 303 | WP_014995878.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| B5T_RS23530 | 3949046..3949345 | + | 300 | WP_014995879.1 | putative addiction module antidote protein | Antitoxin |
| B5T_RS23535 | 3949319..3949756 | - | 438 | WP_202803017.1 | hypothetical protein | - |
| B5T_RS17550 | 3950047..3951897 | - | 1851 | WP_014995881.1 | lipoprotein | - |
| B5T_RS17555 | 3952037..3953269 | - | 1233 | WP_041717716.1 | outer membrane protein transport protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 3937715..3949756 | 12041 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11237.08 Da Isoelectric Point: 10.3147
>T28388 WP_014995878.1 NC_018691:3948747-3949049 [Alcanivorax dieselolei B5]
MKTILTTPEFDDWLQRLRDKQGKAKINARIRRLSLGNPGDIEPVGSGISELRIHYGPGYRVYLMARGLEIIVLLVGGDKK
TQSKDIKAAKALAKQYQEDL
MKTILTTPEFDDWLQRLRDKQGKAKINARIRRLSLGNPGDIEPVGSGISELRIHYGPGYRVYLMARGLEIIVLLVGGDKK
TQSKDIKAAKALAKQYQEDL
Download Length: 303 bp
>T28388 NC_018691:3948747-3949049 [Alcanivorax dieselolei B5]
ATGAAAACGATCCTCACCACCCCAGAGTTTGATGATTGGCTGCAGCGCCTCCGCGATAAGCAGGGCAAGGCCAAGATCAA
TGCCCGCATTCGTCGCCTTTCATTGGGCAACCCGGGCGACATCGAACCTGTAGGCAGTGGGATTAGCGAGCTTCGCATTC
ACTACGGCCCAGGCTATCGCGTGTACCTGATGGCTCGCGGCCTGGAAATCATTGTCCTGCTCGTGGGTGGCGACAAGAAA
ACCCAGAGCAAAGACATCAAAGCGGCCAAGGCGCTTGCGAAGCAATACCAGGAGGACCTATGA
ATGAAAACGATCCTCACCACCCCAGAGTTTGATGATTGGCTGCAGCGCCTCCGCGATAAGCAGGGCAAGGCCAAGATCAA
TGCCCGCATTCGTCGCCTTTCATTGGGCAACCCGGGCGACATCGAACCTGTAGGCAGTGGGATTAGCGAGCTTCGCATTC
ACTACGGCCCAGGCTATCGCGTGTACCTGATGGCTCGCGGCCTGGAAATCATTGTCCTGCTCGTGGGTGGCGACAAGAAA
ACCCAGAGCAAAGACATCAAAGCGGCCAAGGCGCTTGCGAAGCAATACCAGGAGGACCTATGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10876.31 Da Isoelectric Point: 5.9593
>AT28388 WP_014995879.1 NC_018691:3949046-3949345 [Alcanivorax dieselolei B5]
MSNHKLKPWDAADHLEDQEDMILYLNACIDDDPGDGSLIRAALSDIARAQNMSRLAKETGMTRAGLYKALSPDGRPGFDT
MLKITRALGLSLHFDGHAH
MSNHKLKPWDAADHLEDQEDMILYLNACIDDDPGDGSLIRAALSDIARAQNMSRLAKETGMTRAGLYKALSPDGRPGFDT
MLKITRALGLSLHFDGHAH
Download Length: 300 bp
>AT28388 NC_018691:3949046-3949345 [Alcanivorax dieselolei B5]
ATGAGCAACCACAAACTGAAACCATGGGATGCCGCCGATCACCTGGAGGACCAGGAAGATATGATCCTCTATCTGAACGC
CTGCATTGACGACGACCCCGGCGACGGCTCTCTCATCCGGGCAGCGCTGAGCGACATTGCCCGCGCACAGAATATGTCCC
GCCTCGCGAAAGAAACGGGCATGACCCGAGCTGGCCTCTACAAAGCGCTCTCTCCTGATGGCCGGCCTGGGTTCGACACC
ATGCTCAAAATCACCCGTGCCTTGGGGCTGAGCCTACACTTTGATGGGCACGCACACTAA
ATGAGCAACCACAAACTGAAACCATGGGATGCCGCCGATCACCTGGAGGACCAGGAAGATATGATCCTCTATCTGAACGC
CTGCATTGACGACGACCCCGGCGACGGCTCTCTCATCCGGGCAGCGCTGAGCGACATTGCCCGCGCACAGAATATGTCCC
GCCTCGCGAAAGAAACGGGCATGACCCGAGCTGGCCTCTACAAAGCGCTCTCTCCTGATGGCCGGCCTGGGTTCGACACC
ATGCTCAAAATCACCCGTGCCTTGGGGCTGAGCCTACACTTTGATGGGCACGCACACTAA