Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3948747..3949345 Replicon chromosome
Accession NC_018691
Organism Alcanivorax dieselolei B5

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag B5T_RS17535 Protein ID WP_014995878.1
Coordinates 3948747..3949049 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag B5T_RS23530 Protein ID WP_014995879.1
Coordinates 3949046..3949345 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5T_RS17505 3945084..3946058 - 975 WP_041717100.1 type I-F CRISPR-associated endonuclease Cas1 -
B5T_RS17510 3946251..3947228 - 978 WP_014995873.1 YafY family transcriptional regulator -
B5T_RS17515 3947350..3947604 + 255 WP_041717714.1 type II toxin-antitoxin system HicA family toxin -
B5T_RS17520 3947601..3947945 + 345 WP_014995875.1 type II toxin-antitoxin system HicB family antitoxin -
B5T_RS17525 3947993..3948316 - 324 WP_014995876.1 hypothetical protein -
B5T_RS17535 3948747..3949049 + 303 WP_014995878.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B5T_RS23530 3949046..3949345 + 300 WP_014995879.1 putative addiction module antidote protein Antitoxin
B5T_RS23535 3949319..3949756 - 438 WP_202803017.1 hypothetical protein -
B5T_RS17550 3950047..3951897 - 1851 WP_014995881.1 lipoprotein -
B5T_RS17555 3952037..3953269 - 1233 WP_041717716.1 outer membrane protein transport protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3937715..3949756 12041


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-95)

Antitoxin

Uncharacterized protein HI1420

(5-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11237.08 Da        Isoelectric Point: 10.3147

>T28388 WP_014995878.1 NC_018691:3948747-3949049 [Alcanivorax dieselolei B5]
MKTILTTPEFDDWLQRLRDKQGKAKINARIRRLSLGNPGDIEPVGSGISELRIHYGPGYRVYLMARGLEIIVLLVGGDKK
TQSKDIKAAKALAKQYQEDL

Download         Length: 303 bp

>T28388 NC_018691:3948747-3949049 [Alcanivorax dieselolei B5]
ATGAAAACGATCCTCACCACCCCAGAGTTTGATGATTGGCTGCAGCGCCTCCGCGATAAGCAGGGCAAGGCCAAGATCAA
TGCCCGCATTCGTCGCCTTTCATTGGGCAACCCGGGCGACATCGAACCTGTAGGCAGTGGGATTAGCGAGCTTCGCATTC
ACTACGGCCCAGGCTATCGCGTGTACCTGATGGCTCGCGGCCTGGAAATCATTGTCCTGCTCGTGGGTGGCGACAAGAAA
ACCCAGAGCAAAGACATCAAAGCGGCCAAGGCGCTTGCGAAGCAATACCAGGAGGACCTATGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10876.31 Da        Isoelectric Point: 5.9593

>AT28388 WP_014995879.1 NC_018691:3949046-3949345 [Alcanivorax dieselolei B5]
MSNHKLKPWDAADHLEDQEDMILYLNACIDDDPGDGSLIRAALSDIARAQNMSRLAKETGMTRAGLYKALSPDGRPGFDT
MLKITRALGLSLHFDGHAH

Download         Length: 300 bp

>AT28388 NC_018691:3949046-3949345 [Alcanivorax dieselolei B5]
ATGAGCAACCACAAACTGAAACCATGGGATGCCGCCGATCACCTGGAGGACCAGGAAGATATGATCCTCTATCTGAACGC
CTGCATTGACGACGACCCCGGCGACGGCTCTCTCATCCGGGCAGCGCTGAGCGACATTGCCCGCGCACAGAATATGTCCC
GCCTCGCGAAAGAAACGGGCATGACCCGAGCTGGCCTCTACAAAGCGCTCTCTCCTGATGGCCGGCCTGGGTTCGACACC
ATGCTCAAAATCACCCGTGCCTTGGGGCTGAGCCTACACTTTGATGGGCACGCACACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References