Detailed information of TA system TA028386

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2055677..2056214
• Replicon: chromosome
• Accession: NC_018691
• Organism: Alcanivorax dieselolei B5

Toxin (Protein)

• Gene name: relE
• Uniprot ID: K0CF02
• Locus tag: B5T_RS09315
• Protein ID: WP_014994243.1
• Coordinates: 2055677..2055976 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: B5T_RS09320
• Protein ID: WP_041716967.1
• Coordinates: 2055966..2056214 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B5T_RS09290	2050722..2051960	+	1239	WP_014994238.1	branched-chain amino acid ABC transporter permease	-
B5T_RS09295	2051993..2052787	+	795	WP_014994239.1	3-hydroxybutyrate dehydrogenase	-
B5T_RS09300	2053154..2053414	-	261	WP_014994240.1	cell division topological specificity factor MinE	-
B5T_RS09305	2053418..2054230	-	813	WP_014994241.1	septum site-determining protein MinD	-
B5T_RS09310	2054301..2055029	-	729	WP_014994242.1	septum site-determining protein MinC	-
B5T_RS09315	2055677..2055976	-	300	WP_014994243.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
B5T_RS09320	2055966..2056214	-	249	WP_041716967.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
B5T_RS09325	2056449..2056793	+	345	WP_041717466.1	GFA family protein	-
B5T_RS09330	2056885..2058144	-	1260	WP_014994245.1	type II toxin-antitoxin system HipA family toxin	-
B5T_RS09335	2058148..2058453	-	306	WP_014994246.1	helix-turn-helix domain-containing protein	-
B5T_RS09340	2058615..2061074	-	2460	WP_014994247.1	acyl-CoA dehydrogenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-72)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11253.16 Da
• Isoelectric Point: 10.8743

>T28386 WP_014994243.1 NC_018691:c2055976-2055677 [Alcanivorax dieselolei B5]
MTYKLAFKKSALKEWRKLGPSVRDLFKKKLAERLETPHLPSAAVSGGSNLYKIKLRQLGYRLVYSVSDSTVTVIVLAVGK
RNRNEVYDVALSRQEADKR

Nucleotide

• Length: 300 bp

>T28386 NC_018691:c2055976-2055677 [Alcanivorax dieselolei B5]
ATGACCTATAAGCTGGCTTTCAAGAAAAGTGCGTTGAAAGAATGGAGGAAACTCGGCCCCTCAGTCCGCGACCTGTTCAA
GAAAAAGCTGGCGGAAAGATTGGAGACTCCCCATCTCCCTTCCGCTGCGGTCAGCGGTGGCTCCAACTTATATAAAATAA
AGCTACGGCAGCTTGGTTACCGACTGGTTTATTCCGTATCCGACTCCACCGTCACGGTCATTGTCCTCGCCGTGGGTAAG
CGAAATCGAAACGAAGTTTACGACGTCGCACTTTCGCGCCAAGAGGCTGACAAGCGGTAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9146.68 Da
• Isoelectric Point: 4.6127

>AT28386 WP_041716967.1 NC_018691:c2056214-2055966 [Alcanivorax dieselolei B5]
MTHQILTEIAASISELKANPMKVVASGEGMPIAVLNRNEPAFYCIPAKAYEAMMDLIEDKELLELAKRRIKEDSVRVSLD
DL

Nucleotide

• Length: 249 bp

>AT28386 NC_018691:c2056214-2055966 [Alcanivorax dieselolei B5]
ATGACACATCAAATACTTACAGAGATTGCCGCCAGTATCTCGGAGCTAAAAGCAAATCCCATGAAAGTCGTCGCCAGCGG
CGAGGGTATGCCGATTGCCGTTCTCAACAGGAACGAGCCCGCCTTCTATTGCATTCCTGCTAAAGCCTATGAGGCCATGA
TGGACCTCATCGAGGACAAGGAGCTTCTTGAGCTCGCCAAACGTCGCATCAAGGAAGATAGCGTTCGGGTAAGCCTGGAT
GACCTATAA

Structures

Toxin

• AlphaFold DB: K0CF02