Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 2517587..2518209 Replicon chromosome
Accession NZ_CP127251
Organism Devosia sp. YIM 151766

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag O9Z70_RS12410 Protein ID WP_286019761.1
Coordinates 2517587..2517925 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag O9Z70_RS12415 Protein ID WP_286019762.1
Coordinates 2517928..2518209 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O9Z70_RS12385 (O9Z70_12385) 2512956..2513144 + 189 WP_286019757.1 hypothetical protein -
O9Z70_RS12390 (O9Z70_12390) 2513235..2514386 - 1152 WP_286019758.1 tRNA 2-thiouridine(34) synthase MnmA -
O9Z70_RS12395 (O9Z70_12395) 2514629..2516077 + 1449 WP_286019759.1 flagellar hook-length control protein FliK -
O9Z70_RS12400 (O9Z70_12400) 2516090..2516812 + 723 WP_286019760.1 flagellar hook assembly protein FlgD -
O9Z70_RS12405 (O9Z70_12405) 2517211..2517489 + 279 WP_035085775.1 DUF1153 domain-containing protein -
O9Z70_RS12410 (O9Z70_12410) 2517587..2517925 - 339 WP_286019761.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
O9Z70_RS12415 (O9Z70_12415) 2517928..2518209 - 282 WP_286019762.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
O9Z70_RS12420 (O9Z70_12420) 2518478..2520118 + 1641 WP_286019763.1 flagellar basal-body MS-ring/collar protein FliF -
O9Z70_RS12425 (O9Z70_12425) 2520124..2521200 + 1077 WP_286019764.1 flagellar motor switch protein FliG -
O9Z70_RS12430 (O9Z70_12430) 2521205..2521876 + 672 WP_286019765.1 FliH/SctL family protein -
O9Z70_RS12435 (O9Z70_12435) 2521927..2522217 + 291 WP_286022010.1 flagellar motor switch protein FliN -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-109)

Antitoxin

SpoVT-AbrB domain

(14-58)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12135.94 Da        Isoelectric Point: 9.2676

>T283685 WP_286019761.1 NZ_CP127251:c2517925-2517587 [Devosia sp. YIM 151766]
MERGEIWYIDLSPAAGREPQGRHPVLVISPRAFNRSGMALVAPITTIGKASRMRGFAVNLQGAGTATTGVIQCDAIRVVD
MVQRNARQDRDRDAVPPDILDDVLARIATIAQ

Download         Length: 339 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10254.82 Da        Isoelectric Point: 6.7174

>AT283685 WP_286019762.1 NZ_CP127251:c2518209-2517928 [Devosia sp. YIM 151766]
MTAHPGYLTKTRLKKAGGSLIVTVPAAARHSLLLREGQELAVSIEGDRLILQPVAKTPRYRLEDLMGQCELDASHPDETR
DWLDAPPVGREIL

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References