Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 240565..241187 Replicon chromosome
Accession NZ_CP127244
Organism Salinicola sp. JS01

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag QO259_RS01255 Protein ID WP_081919087.1
Coordinates 241005..241187 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag QO259_RS01250 Protein ID WP_035470482.1
Coordinates 240565..240984 (-) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QO259_RS01220 (QO259_01220) 235573..236373 - 801 WP_285951497.1 hypothetical protein -
QO259_RS01225 (QO259_01225) 237429..237779 + 351 WP_285951498.1 hypothetical protein -
QO259_RS01230 (QO259_01230) 237790..238182 - 393 WP_207034487.1 type II toxin-antitoxin system HicB family antitoxin -
QO259_RS01235 (QO259_01235) 238186..238374 - 189 WP_285951499.1 type II toxin-antitoxin system HicA family toxin -
QO259_RS01240 (QO259_01240) 238563..239564 - 1002 WP_285951500.1 endonuclease -
QO259_RS01245 (QO259_01245) 239726..240445 + 720 WP_285951501.1 hypothetical protein -
QO259_RS01250 (QO259_01250) 240565..240984 - 420 WP_035470482.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
QO259_RS01255 (QO259_01255) 241005..241187 - 183 WP_081919087.1 type II toxin-antitoxin system HicA family toxin Toxin
QO259_RS01260 (QO259_01260) 241272..242273 - 1002 WP_285951502.1 contractile injection system protein, VgrG/Pvc8 family -
QO259_RS01265 (QO259_01265) 242270..242713 - 444 WP_035470479.1 phage tail protein -
QO259_RS01270 (QO259_01270) 242743..245022 - 2280 WP_285951503.1 phage tail tape measure protein -
QO259_RS01275 (QO259_01275) 244976..245140 - 165 WP_285951504.1 GpE family phage tail protein -
QO259_RS01280 (QO259_01280) 245191..245550 - 360 WP_285951505.1 phage tail assembly protein -
QO259_RS01285 (QO259_01285) 245635..246147 - 513 WP_035474376.1 phage major tail tube protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gnd 215776..267721 51945


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(4-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-128)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6697.76 Da        Isoelectric Point: 11.3261

>T283682 WP_081919087.1 NZ_CP127244:c241187-241005 [Salinicola sp. JS01]
VDSRALIRELERDGWALVRVNGSHHHFRHPIKPGTVTVPHPKKDLKTGLVKGIRKSAGLD

Download         Length: 183 bp

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15150.13 Da        Isoelectric Point: 4.5151

>AT283682 WP_035470482.1 NZ_CP127244:c240984-240565 [Salinicola sp. JS01]
MLFPIAIERGDAQHAYGVAVPDLPGCFSAGDTLEEALANVHEAIAGWLETAVDVGDPIPQATSLEHHLDNPDFAGWIWAV
VDIDVTPYLGKSHKINVTLPDLLVKRIDEFVATHDGDKTRSGFLARIALQELTRARKDV

Download         Length: 420 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References