Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2014046..2014191 Replicon chromosome
Accession NZ_CP127235
Organism Klebsiella pneumoniae strain 130128

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2014082..2014184 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2014046..2014191 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRA17_RS09870 (QRA17_09870) 2009176..2011236 + 2061 WP_004151449.1 oligopeptidase B -
QRA17_RS09875 (QRA17_09875) 2011240..2011899 - 660 WP_002911407.1 exodeoxyribonuclease X -
QRA17_RS09880 (QRA17_09880) 2011978..2012208 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QRA17_RS09885 (QRA17_09885) 2012321..2012695 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QRA17_RS09890 (QRA17_09890) 2012699..2013568 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
QRA17_RS09895 (QRA17_09895) 2013585..2013923 + 339 WP_002911404.1 YebY family protein -
- 2014046..2014191 - 146 - - Antitoxin
- 2014082..2014184 + 103 - - Toxin
QRA17_RS09900 (QRA17_09900) 2014559..2014702 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QRA17_RS09905 (QRA17_09905) 2014807..2015775 - 969 WP_004151446.1 VirK/YbjX family protein -
QRA17_RS09910 (QRA17_09910) 2015932..2016585 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QRA17_RS09915 (QRA17_09915) 2016582..2016773 - 192 WP_002911395.1 YebW family protein -
QRA17_RS09920 (QRA17_09920) 2016871..2017110 - 240 WP_002911393.1 YebV family protein -
QRA17_RS09925 (QRA17_09925) 2017226..2018659 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T283659 NZ_CP127235:2014082-2014184 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT283659 NZ_CP127235:c2014191-2014046 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References