Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4323991..4324136 Replicon chromosome
Accession NZ_CP127229
Organism Klebsiella pneumoniae strain 130119

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4324027..4324129 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4323991..4324136 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QRA14_RS21025 (QRA14_21025) 4319121..4321181 + 2061 WP_004151449.1 oligopeptidase B -
QRA14_RS21030 (QRA14_21030) 4321185..4321844 - 660 WP_002911407.1 exodeoxyribonuclease X -
QRA14_RS21035 (QRA14_21035) 4321923..4322153 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QRA14_RS21040 (QRA14_21040) 4322266..4322640 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QRA14_RS21045 (QRA14_21045) 4322644..4323513 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
QRA14_RS21050 (QRA14_21050) 4323530..4323868 + 339 WP_002911404.1 YebY family protein -
- 4323991..4324136 - 146 - - Antitoxin
- 4324027..4324129 + 103 - - Toxin
QRA14_RS21055 (QRA14_21055) 4324504..4324647 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QRA14_RS21060 (QRA14_21060) 4324752..4325720 - 969 WP_004151446.1 VirK/YbjX family protein -
QRA14_RS21065 (QRA14_21065) 4325877..4326530 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QRA14_RS21070 (QRA14_21070) 4326527..4326718 - 192 WP_002911395.1 YebW family protein -
QRA14_RS21075 (QRA14_21075) 4326816..4327055 - 240 WP_002911393.1 YebV family protein -
QRA14_RS21080 (QRA14_21080) 4327171..4328604 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T283641 NZ_CP127229:4324027-4324129 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT283641 NZ_CP127229:c4324136-4323991 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References