Detailed information of TA system TA283632

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Acetyltransf_4(toxin)
• Location: 5838281..5839689
• Replicon: chromosome
• Accession: NZ_CP127228
• Organism: Pseudomonas tohonis strain KRS022

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: QQ016_RS26230
• Protein ID: WP_263150773.1
• Coordinates: 5838281..5838850 (+)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: QQ016_RS26235
• Protein ID: WP_285961036.1
• Coordinates: 5838847..5839689 (+)
• Length: 281 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QQ016_RS26225	5834553..5838029	-	3477	WP_285961035.1	PAS domain-containing hybrid sensor histidine kinase/response regulator	-
QQ016_RS26230	5838281..5838850	+	570	WP_263150773.1	GNAT family protein	Toxin
QQ016_RS26235	5838847..5839689	+	843	WP_285961036.1	AraC family transcriptional regulator	Antitoxin
QQ016_RS26240	5839727..5840440	+	714	WP_285961037.1	AzlC family ABC transporter permease	-
QQ016_RS26245	5840440..5840769	+	330	WP_213625826.1	AzlD domain-containing protein	-
QQ016_RS26250	5840922..5842796	+	1875	WP_173171964.1	MFS transporter	-
QQ016_RS26255	5842860..5843174	-	315	WP_263150769.1	quaternary ammonium compound efflux SMR transporter SugE	-
QQ016_RS26260	5843322..5844269	-	948	WP_173171968.1	bile acid:sodium symporter family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (14-146)

Antitoxin

• DNA binding HTH domain, AraC-type (194-271)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21249.20 Da
• Isoelectric Point: 6.8864

>T283632 WP_263150773.1 NZ_CP127228:5838281-5838850 [Pseudomonas tohonis]
MFNPQPVILQRGALRLEPLGEADVTELSALAEANRDELVYMSGPLRPDWYRQGLAEQREGQAVVFAIRLGDRLVGTSRFA
DFMPALPAVEIGWTWLARSEHASGLNASIKYLMLRHAFEEWQVVRVQLKTAGSNLRSQKAIEKLGAQREGVLRNHRRLAD
GRLDDSVLYSITDHEWPAVKQALEASFGQ

Nucleotide

• Length: 570 bp

Antitoxin

Protein

• Length: 281 a.a.
• Molecular weight: 31151.51 Da
• Isoelectric Point: 8.2125

>AT283632 WP_285961036.1 NZ_CP127228:5838847-5839689 [Pseudomonas tohonis]
MSAGGERTRFWQASALGGVELLHARYIEQRFSPHVHEGYVFTVLESGAQRFRHRGSDHLAAVGSMVLINPDELHTGSKAH
EEGWRYRGFYPDLHRVTEVLDELEIATGGLPTFADSVLHDPEVTRRFLDLHRLLECNASALEQQVAWREAILLLFSRHAC
IGAPRPAGQEPHAVALAREMLAARLASPPSLEELAALVGLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLREGCAPL
PVAMQLGFADQSHLTRQFKQAYGVGPGEYRSACARSFKTG

Nucleotide

• Length: 843 bp