Detailed information of TA system TA283631

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 5825675..5826834
• Replicon: chromosome
• Accession: NZ_CP127228
• Organism: Pseudomonas tohonis strain KRS022

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: QQ016_RS26185
• Protein ID: WP_263150781.1
• Coordinates: 5826082..5826834 (+)
• Length: 251 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: QQ016_RS26180
• Protein ID: WP_111264584.1
• Coordinates: 5825675..5826046 (+)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QQ016_RS26150	5821019..5821570	-	552	WP_285961029.1	GNAT family N-acetyltransferase	-
QQ016_RS26155	5822065..5823663	+	1599	WP_285961030.1	M28 family metallopeptidase	-
QQ016_RS26160	5823765..5824214	+	450	WP_263150784.1	S24 family peptidase	-
QQ016_RS26165	5824238..5824423	-	186	WP_228723486.1	hypothetical protein	-
QQ016_RS26170	5824617..5825018	-	402	WP_263150783.1	hypothetical protein	-
QQ016_RS26175	5825069..5825551	-	483	WP_263150782.1	transcription elongation factor GreAB	-
QQ016_RS26180	5825675..5826046	+	372	WP_111264584.1	DUF2384 domain-containing protein	Antitoxin
QQ016_RS26185	5826082..5826834	+	753	WP_263150781.1	RES family NAD+ phosphorylase	Toxin
QQ016_RS26190	5826831..5827886	+	1056	WP_285961031.1	AraC family transcriptional regulator	-
QQ016_RS26195	5828234..5828641	+	408	WP_111264581.1	SEL1-like repeat protein	-
QQ016_RS26200	5828805..5830169	+	1365	WP_271106364.1	DNA recombination protein RmuC	-
QQ016_RS26205	5830240..5831124	-	885	WP_285961032.1	metal-dependent hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (58-206)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (72-121)

Sequences

Toxin

Protein

• Length: 251 a.a.
• Molecular weight: 28153.17 Da
• Isoelectric Point: 7.1064

>T283631 WP_263150781.1 NZ_CP127228:5826082-5826834 [Pseudomonas tohonis]
MDIWTTCQGPQHVGPLRGRLVRLVESQEQVATLQLVDNLAEQALLEELIETSKPPLPRSAEPLHYLLKTPFRYPPLRWGS
RFGTVHEPSLFYAASRLETAMAEGAFYRFVLWSGMAVPPPSGRILSEHSSFEARFQVERGVQLQLPPFDRHAQALADPVD
YRASQALGAAMRAAGVEAFEYRSARCPLQGTNIALFTPEAFTERRPRNLTPWLCETTAEYVAFKHAQAPDTPRLFRMTQF
LIDGHLPQPA

Nucleotide

• Length: 753 bp

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13570.78 Da
• Isoelectric Point: 10.2920

>AT283631 WP_111264584.1 NZ_CP127228:5825675-5826046 [Pseudomonas tohonis]
MSALSRPTLDPDAVLAKALLNTREQLGLTQQQLADIVGVHRTAITRWADSGGIRPQSKTGELALLLIRAYRALFALFGGN
LDDMRHFLRTENRHLGAVPLELMGQVQGLVRVVEYLDAIRGKI

Nucleotide

• Length: 372 bp